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Buy Trimix Injections

Trimix - Treatment Plan Image


Buy Trimix Injections

Trimix boasts a 95% success rate in treating erectile dysfunction swiftly within 5-15 minutes. This potent injection provides firm, enduring erections for hours, enhancing your intimate experiences remarkably.
Benefits of Trimix
  • Up to 95% Effective in Treating ED
  • Take 10 mins before intercourse
  • Lasts 1-2 hours
  • Best for resistant ED
Dosage Information

Varying strengths customized for your needs

Common Trimix Side Effects
  • Pain or redness at the injection site
  • Bruising at the injection site may occur
  • Erection lasting more than four hours (priapism)

What’s Included

When you buy Trimix from Invigor Medical, rest assured that you are working with a licensed, experienced, and dedicated doctor and receiving Trimix from a U.S.-based, FDA 503B-registered pharmacy.
Rx Consultation

Discuss your treatment plan with one of our licensed practitioners.


All medications and supplies included, no hidden fees.


Our well-trained medical staff are ready to answer your questions. 

1 Vial
2 Vials
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Erectile Dysfunction: The Best Available Treatments

Benefits of Trimix

Trimix injections are a highly effective ED treatment option for men of all ages, including those with diabetes and cardiovascular disease. Bimix and QuadMix provide alternative medication combinations for men who may have sensitivities to prostaglandin E1 or who benefit from adding atropine.

  • Trimix
    Improves Erectile Function
  • Trimix
    Increases Confidence
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What users are saying about Trimix

Do I Need Trimix?


You may be experiencing a combination of the following symptoms
  • Erectile Dysfunction
If you are experiencing any of the symptoms listed above, you may be eligible for Trimix. After you fill out the forms to get started, an Invigor Medical specialist will contact you.

Trimix FAQs

The Medication
How many units of Trimix should I take?

Trimix dosage can vary widely from person to person, and several variables help your doctor determine a good starting point. Most patients start by using around five units of TriMix and then increase the dosage in small increments each time until a hard, sustained erection is achieved.

How often can I use Trimix injections?

Most men can inject Trimix up to three times per week, with 24 hours between each injection. Injecting more often than this can cause penile scarring.

Does Trimix work better than Viagra?

Trimix is more effective than Viagra based on the percentage of men who report that their ED is improved. The success rate for Trimix is 80% to 95%. Viagra is around 60% to 70% effective for men with moderate ED.

More men use Viagra than Trimix because taking a pill is easier than doing a penile self-injection. However, men using Trimix report that the injection procedure is nearly painless, and the results are fast and consistent.

Many men, especially those taking medications for heart disease, cannot take Viagra or other medications in that class. For these men and men who want an ED treatment option that is unaffected by diet or alcohol consumption, Trimix is a great option.

Are injections better than pills for ED?

The American Urological Association recommends a process of shared decision-making when deciding which treatment option to use for ED.

Men should be offered a full range of treatment options. Some men have medical conditions or are taking medications that keep them from taking ED pills. For these men, ED injections are a highly effective option.

Do Trimix injections lose effectiveness?

Trimix may not work for all men, including men with the following conditions:

  • Penile scarring
  • Peyronie’s disease
  • Poorly controlled diabetes
  • Dialysis-dependent kidney disease
  • Severe venous leak syndrome

Talk to your healthcare provider if Trimix does not work for you. You may need a dosage change. They may also need to review your injection technique to ensure the medication is being delivered into the corpora cavernosa. Also, check the expiration date on your Trimix and ensure that you are storing it correctly.

What is the difference between Trimix and Caverject?

Trimix is a combination of three medications that work synergistically to increase blood flow into the penis and produce an erection. The three medications in Trimix are:

  • Prostaglandin
  • Papaverine
  • Phentolamine

Caverject only contains prostaglandin.

What happens if you inject Trimix too often?

Trimix should always be injected following your healthcare provider’s instructions. If Trimix is injected too frequently or at too high a dose, it could cause priapism.

Priapism is an erection that lasts longer than four hours. A prolonged erection allows blood to sit in the penis for too long. Fresh blood is needed to replenish oxygen and nutrients and remove waste products. Untreated priapism can damage the penis.

How often can I inject Trimix?

It is important to follow the instructions provided by your healthcare provider and pharmacist.

In general:

  • Trimix should never be injected more than once in a 24-hour period.
  • Trimix should not be injected for more than two consecutive days.
  • Trimix should not be injected more than three times in one week.
How is Trimix stored?

Trimix must be stored refrigerated at 36°F–46°F. Extra Trimix vials can be frozen. Keep Trimix away from light and extreme temperatures. Discard expired medication properly.

Detailed storage instructions are usually included with your Trimix prescription, as they may vary between compounding pharmacies.

Who should not use Trimix?

Those with a known hypersensitivity to Trimix or any of its components, sickle cell disease, sickle cell trait, multiple myeloma, leukemia, or other blood disorders, a penile implant or prosthesis, penile scarring or anatomical deformities, or a history of priapism should not take Trimix. Don’t take Trimix if you take blood thinners. 

Can you take Trimix with oral ED medications?

Trimix should not be used in conjunction with other ED therapies without consulting with your healthcare provider.

Sometimes, they are used together, but doing so increases the risk of side effects.

Invigor Medical
Do I need a prescription before I buy from Invigor Medical?

No, Invigor Medical employs doctors licensed in all 50 states, and a medical consultation is included with each medical service. Each patient will receive a valid prescription, which is sent to the pharmacy to be filled.

How long does it take to get my medication?

Once you have enrolled for medical services with Invigor Medical, it usually takes 7-14 business days before items arrive at your home. This process includes an online medical consultation, prescription approval, the medication getting filled at the pharmacy, and the medication being sent to your home.

More Questions?
Fill out the form below, and one of our treatment specialists will contact you.

Trimix Overview

Trimix is a highly effective injectable used to treat erectile dysfunction (ED). Trimix is a compounded medication with three active ingredients: alprostadil, phentolamine, and papaverine. It is only available by prescription.

All three medications in Trimix synergistically widen blood vessels, increasing blood flow into the penis, resulting in a firm and long-lasting erection. According to clinical studies, 87% to 93% of men who use Trimix are satisfied with the results. Lower medication doses can be used when medications are combined in Trimix, resulting in fewer side effects.

Trimix is injected directly into the penis using a very small needle. When used properly under medical supervision, injectable ED medications have been safe ED treatment options for over 40 years. Trimix provides an excellent solution for men who do not get optimal results from oral ED medications.

What is Trimix?

Why do Patients Love Trimix?

Patients who get Trimix shots from Invigor Medical experience consistent results. Three important benefits are listed below.


Trimix has been shown to be nearly 95% effective in treating erectile dysfunction.


In as little as 5 to 15 minutes, Trimix users can get an erection firm enough to perform sexual activities.


Trimix injections can make an erection firm and long-lasting enough for sexual penetration.

Trimix is a Combination of Three Medications That Increase Blood Flow into the Penis

Trimix is an injectable ED treatment option. It is a compound made up of three medications: phentolamine, papaverine, and alprostadil (prostaglandin E1)

It is an excellent ED treatment alternative for men who can’t or don’t want to take oral ED medications, have had severe side effects, or haven’t had successful results when taking oral ED medications.

The three medications in Trimix work together to increase blood flow to the penis. Based on clinical studies, the success rate for Trimix when treating ED approaches 95%.

According to the American Urological Association, 53.7% to 100% of men (depending on the population) achieved a satisfactory erection with Trimix, and 46.3% to 98.8% of men were happy with their choice to use intracavernosal injections as a treatment option.

Other Injectable ED choices

Although Trimix is a frequently prescribed injectable to treat ED and is highly effective, it is not the only option.


Bimix is a combination of phentolamine and papaverine. It is an excellent choice for men with sensitivity to prostaglandin E1 or who have health conditions that contraindicate its use.


QuadMix combines phentolamine, papaverine, atropine, and alprostadil (prostaglandin E1). Trimix is up to 95% effective in treating ED. If you are among the other 5% of men, Quadmix may be a great option.

The Science of Trimix

An erection occurs through a complex physiological process requiring coordination between the brain, hormones, nerves, blood vessels, and penile tissues. An erection occurs when blood flows into the spongy tissue in the penis and becomes trapped in spaces known as the corpora cavernosa. As blood fills these chambers, pressure builds, causing the penis to stiffen. 

Trimix is a combination of three medications: phentolamine, papaverine, and prostaglandin E1 (alprostadil).


The alpha-adrenergic antagonist phentolamine relaxes the smooth muscle lining the spongy tissue in the penis. This allows blood to flow into the penis, leading to a firmer erection.


Papaverine, one of the first injectable medications used to treat ED, is a vasodilator, which means that it dilates blood vessels and increases blood flow into the penis. Papaverine is no longer used to treat ED on its own. It is used in conjunction with phentolamine and prostaglandin to improve ED treatment outcomes while minimizing side effects.

Prostaglandin E1 (alprostadil) 

Prostaglandin E1 relaxes smooth muscle surrounding blood vessels in the penis and the spongy tissue in the penis, allowing them to fill with blood. Blood becomes entrapped in the penis, which leads to an erection. Pellets inserted into the urethra or by penile injection are two ways to administer prostaglandin.

How Does Trimix Work?

Trimix Increases Blood Flow to the Penis

The three ingredients in Trimix—alprostadil, papaverine, and phentolamine—work in combination to increase blood flow to the penis, which causes a hard erection.

Alprostadil Graphic


Papaverine Graphic


Phentolamine Graphic


Papaverine Increases Blood Flow into the Penis

Papaverine is an alkaloid that increases the production of cAMP, a molecule that eases the tension in the smooth muscle that lines the corpora cavernosa and the walls of blood vessels. Its mechanism is not completely understood because it appears to act on several pathways.

When papaverine is injected into the intracavernosal space of the penis, it increases blood flow, producing an erection. Papaverine also relaxes the smooth muscle lining the corpora cavernosa in the penis, allowing them to fill more completely.

Prostaglandin E1 (Alprostadil) Increases Blood Flow into the Penis

Prostaglandin E1 (alprostadil) is a synthetic form of prostaglandin, a potent vasodilator. Prostaglandin E1 relaxes the smooth muscle lining the corpora cavernosa in the penis by activating prostaglandin receptors and subsequently increasing cyclic monophosphate levels in the smooth muscle. This causes a decrease in calcium levels in the smooth muscles, allowing them to relax and fill with blood.

Prostaglandin E1 also relaxes the smooth muscle lining blood vessels that enter the penis, allowing for greater blood flow into the penis.

Phentolamine Increases Blood Flow into the Penis

Phentolamine is an alpha-adrenoceptor antagonist, which means that it blocks chemicals such as epinephrine and norepinephrine from binding to alpha-adrenergic receptors. Competitively binding to alpha-adrenergic receptors, phentolamine causes smooth muscle relaxation and blood vessel dilation, causing penile erection. When blood vessels are widened, blood pressure decreases, and blood flow into the penis increases.

Included with the Plan


Free Doctor Consult

The consultation with the doctor is always included when you sign up for Trimix.

Medical Support

Our friendly staff are knowledgeable and available to answer any questions.

Supplies Included

When you purchase Trimix, all required supplies are always included.

No Doctors Office

Skip the in-person doctor’s visit, consult remotely, and get Trimix shipped directly to you.

Licensed Pharmacies

Our U.S. based, FDA-registered pharmacies provide quality meds tested for purity and potency.

No Hidden Fees

Our licensed doctors cover all 50 states and are very well versed with the medications we offer.

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Trimix Dosage: How Many Units Of Trimix Should I Take?
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Everything You Need To Know About Trimix Injections
This article will serve as a guide to frequently asked questions about Trimix injections. It will cover basic information such as what Trimix is and what it is used to treat for curious but casual...
At What Age Does Erectile Dysfunction Start?
Erectile dysfunction is the inability to get and maintain an erection firm enough for satisfactory sexual performance. An isolated incident of ED is normal and is common; however, approximately 18...