PT-141 stimulates melanocortin receptors in the brain in an area of the brain that affects sexual behavior. It increases libido in men and women and improves erectile function in men. PT-141 is also used to treat female sexual arousal disorder.

PT-141 is a prescription medication. If you are interested in PT-141, you will be asked to complete medical forms on the secure Invigor Medical platform. After completing these forms, you will meet with an Invigor Medical healthcare professional. If you have no contraindications to using PT-141, they will prescribe it and arrange for it to be delivered from one of our partner pharmacies.

PT-141 was developed from the Melanotan II peptide. When researchers explored the use of this peptide as a tanning agent, they noted an unusual side effect—increased libido and spontaneous erections. While it still promotes skin tanning, PT-141 is prescribed for its other effects: improving libido in men and women, improving erectile function, and treating hypoactive sexual arousal disorder.

PT-141 is injected just under the skin in fatty tissue, typically the skin on the lower right side of the abdomen. PT-141 is injected at least 45 minutes before sexual activity.

PT-141 is also available as a nasal spray.

PT-141 is currently FDA-approved to treat female hypoactive sexual desire disorder in premenopausal women. PT-141 is also used to treat decreased libido in men and women and erectile dysfunction in men.

Female arousal disorder or female hypoactive sexual desire disorder describes a condition in which women have little or no interest in sex. Women with this condition do not respond psychologically or physically to sexual stimulation. It is only considered a medical condition if the affected woman is distressed by the lack of arousal.

Based on DSM-5 criteria, sexual arousal disorder can be diagnosed when there is a decrease in  three or more of the following:

• Sexual or erotic fantasies or thoughts
• Interest or arousal in response to erotic stimuli, whether internal or external
• Interest in sexual activity
• Pleasure or excitement during sexual activity (3/4ths of the time)
• Genital or nongenital sensations (3/4ths of the time)
• Initiating sexual activity or responding when a partner initiates sexual activity

Yes, PT-141 (bremelanotide) is a synthetic analogue of melanocyte-stimulating hormone and is the active metabolite of Melanotan 2.

Clinical trials have demonstrated the safety and effectiveness of combining PT-141 and sildenafil (Viagra). Investigators found that the combination (PT-141 and sildenafil) significantly increased erectile activity when compared to either drug used alone. Using PT-141 and sildenafil together did not cause any new side effects or increase the frequency of side effects when compared to using only one of the drugs.