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Bottle of Passion+
In Stock

Buy Passion+ Online


Enhance your sexual health with a powerful combination of oxytocin, PT-141, and tadalafil. Passion + boosts libido and sexual satisfaction while treating resistant ED.
$300 per Month
Benefits of Passion+
  • Increases libido
  • Better erectile function
  • Supports social bonding
  • Reduces anxiety
  • Improves premature ejaculation
  • Reduces appetite and cravings
Passion+ Dosage Info
  • One troche
  • Oxytocin 100iu, PT-141 2mg, tadalafil 10 mg
What’s Included?
  • Rx Consultation
  • Supplies
  • Support

Quality Tested Products
Us Based Pharmacies
Licensed Physicians
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What is Passion+?

Passion+ combines tadalafil, a PDE-5 inhibitor that increases blood flow to treat ED; oxytocin, a hormone and signaling molecule that promotes social bonding and feelings of connectedness; and PT-141, a synthetic peptide that acts in the brain to improve erectile function and sexual desire.
Hand Holding a Bottle of Passion+

Best Uses for Passion+

Modulates appetite and cravings

Oxytocin helps regulate food intake and energy expenditure. Oxytocin reduces appetite by lowering caloric intake, promoting fat burning for energy, maintaining energy expenditure after weight loss, improving insulin sensitivity, and increasing satiety. Oxytocin may preferentially decrease cravings for high-fat and high-carbohydrate foods. The exact mechanism by which oxytocin affects appetite is unknown, but it may influence hunger and reward pathways in the brain.

Reduces anxiety

Oxytocin plays a crucial role in regulating various social reactions, such as anxiety, aggression, and fear. After reviewing 15 studies, researchers concluded the evidence for using oxytocin to treat anxiety and depression remains inconclusive because of the complexities of treating these conditions.

Increases libido

PT-141 increases physical arousal and genital circulation in both men and women, improving sensation and function. Two identical phase 3, randomized, double-blind, placebo-controlled, multicenter clinical trials evaluated the safety and efficacy of PT-141 in treating hypoactive sexual desire disorder in premenopausal women.

Better erectile function

Passion+ combines PT-141 and tadalafil, two proven medications to treat ED. In a double-blinded placebo-controlled study, approximately 80% of men developed an erection satisfactory for intercourse after using PT-141, and 68% of men reported an increase in sexual desire. Tadalafil has about a 70% success rate regardless of dosage interval.

Supports social bonding

Oxytocin plays an important role in social cognition and behavior. It promotes peer recognition and bonding behaviors. Oxytocin can improve eye contact, emotional recognition, and feelings of trust in relationships. Oxytocin levels increase with sexual or nonsexual touch.

Improves premature ejaculation

Tadalafil increases blood flow to the penis, improving erectile function. It can also prolong ejaculation latency time. Increased blood flow to the penis may change sensory feedback mechanisms and delay ejaculation.
What do patients say about Invigor Medical
  • Just N Review

    Just N

    This process was one of the easiest. From the time of purchase to completing the medical forms and receiving a phone call, it was less than an hour. They were easy to understand, knowledgeable, and allowed me time to ask questions. I left the phone call feeling confident about what to expect and the timeframe of events.
  • Joselys P Review

    Joselys P

    My experience was great! They called me and explained everything I needed to know regarding Semaglutide and the whole process. Very comforting experience.
  • Jeremiah S Review

    Jeremiah S

    I have been a patient of Invigor Medical for about 2 years, and I have always received prompt responses from everyone, from salespeople to physicians… I just refilled my medication today, and it took about 5 text messages to get it taken care of. Thank you for helping me grow older without getting old.
  • Annie Review


    I love Invigor Medical! They have the best customer service ever and wonderful products. Highly recommend this company!!!
  • OKC Couple Review

    OKC Couple

    I’ve been a client of Invigor Medical for several years and always have top notch service. They don’t make you feel weird about the products or any questions you might have. I just did another refill, Kristine C. helped my out and everything took just a few minutes and we were all set. Thank you again!!
  • Carl S Review

    Carl S

    Super easy to work with, I received a helpful call a few minutes after submitting my initial request and thry answered all my questions. So far so good!
  • Jeff K Review

    Jeff K

    Brooklyn has been my point of contact and she has been really great to work with! She is responsive, caring, easy to work with, and friendly! Definitely recommend!
  • Mario C Review

    Mario C

    Always super knowledgeable about all their peptides and other offerings. Great customer service as well!
  • Michelle R Review

    Michelle R

    I’ve never ordered medication this way but I’ve been pleasantly surprised with the ease of the process. Brooklyn has been amazing in helping me to navigate ordering and decide which medications I should discuss with the provider.
  • Mark E Review

    Mark E

    I have been working with Invigor Medical for about a year now. Kudos to Aryanna for doing a very good job. She helps me get my order approved, offers options, and my order is correct and shipped out efficiently. I recommend this company.
  • Jonathan M Review

    Jonathan M

    I have been working with Invigor Medical for several months, and find their service to be excellent. Today I was contacted by Courtney, who was checking in to see how things were going. She was very nice and helped me to save money on my semaglutide injections by switching to a 2 month subscription. Thank you Courtney! You were so kind and helpful.
  • Jen R Review

    Jen R

    **UPDATE** IT’S THE REAL THING! Semaglutide order arrived within a week. All supplies included with very thorough instructions. Extremely noticeable reduction in appetite. Will DEFINITELY buy from Invigor again!
  • Afeistyone Review


    A fantastic organization! Great customer support from the beginning to the end of the process. However, I must highlight one in particular who went above and beyond Brooklyn. She kept me informed and in the know of my order. I appreciate the extra mile at every stage. I would recommend them unreservedly.
  • Guido M Review

    Guido M

    Everyone I have dealt with here has been helpful, respectful, and hard working. Particularly treatment specialist Melissa – making sure that I get the assistance I need. It has been a very pleasant experience.
  • Murrell S Review

    Murrell S

    They were nice, helpful and fast. The service rep that helped me was awesome!
  • Lacey H Review

    Lacey H

    Katie was super helpful and knowledgeable when placing a refill order. She processed the order within a few mins via the chat option. Very easy! Have ordered several times and it’s always been super easy and very reliable! Sign up for the auto-fill, it makes things super nice!!
  • Steven C Review

    Steven C

    Exceptional service from this company. I had a few questions so I contacted Them via web chat on their website. Right after I ended the chat I was very surprised to have received a call from Aryanna, one of the staff there. She was sweet, polite, informative and was able to answer every concern I had ended the chat with. So far my experience here has been excellent.
  • Florenda B Review

    Florenda B

    I highly recommend this business! They are reliable, honest, and operate with integrity. Their products are consistently outstanding, and they constantly exceed my expectations, every time I purchase from them! So, it should go without saying that their customer service is second to none!
    What’s Included
    • Rx Consultation
      Discuss your treatment plan with one of our licensed practitioners.
    • Supplies
      All medications and supplies included, no hidden fees.
    • Support
      Our well-trained medical staff are ready to answer your questions.
    Passion+ Bottle with Two Tablets

    How to use Passion+

    Dissolve one troche between cheek and gum as directed.

    Common Side Effects
    • Headache
    • Flushing
    • Indigestion
    • Nasal congestion
    • Back pain
    • Muscle aches
    • Limb pain
    • Increased thirst
    • Increased urination
    • Constipation
    • Mild fatigue
    • Lightheadedness
    • Nausea
    • Dizziness
    • Vomiting
    • Cough
    • Fatigue
    • Numbness and tingling
    This test detects endotoxins (remnants of bacterial cell walls that can cause serious health problems) in pharmaceutical products. It helps ensure that medications are not contaminated by bacteria. Endotoxin limits are set based on how the medication is administered.
    pH Test
    This test measures the percent hydrogen (pH) or acidity or alkalinity of a product. The pH can affect the medication’s stability, solubility, and potency. To ensure the validity of the endotoxin test, the pH must be kept in a specified range.
    Sterility Test
    This test confirms that all sterile compounded medications are free from microbial contamination, including bacteria and fungi. Sterility testing reduces the risk of infections from taking medications.
    Potency Test
    This test measures the strength or the concentration of an active pharmaceutical ingredient (API) over time. It can be used in conjunction with stability testing to ensure that the medication will retain its potency until its beyond-use date.
    Invigor’s Commitment to Quality Medication
    Our partner compounding pharmacies work with a registered and certified third-party lab to run quality control checks for every lot of compounded medications prescribed and delivered to our patients. These labs follow guidelines to ensure compounded medication safety and quality.
    Invigor’s Commitment to Quality Medication
    Our partner compounding pharmacies work with a registered and certified third-party lab to run quality control checks for every lot of compounded medications prescribed and delivered to our patients. These labs follow guidelines to ensure compounded medication safety and quality.
    This test detects endotoxins in pharmaceutical products to prevent contamination by bacterial remnants, ensuring medication safety. Limits are set based on administration methods.
    pH Test
    This test assesses a product’s pH, which impacts stability, solubility, and potency. Maintaining pH within a specified range ensures the validity of the endotoxin test.
    Sterility Test
    This test ensures sterile compounded medications are free from microbial contamination, minimizing infection risks.
    Potency Test
    This test assesses the potency of an active pharmaceutical ingredient (API) over time, ensuring medication retains potency until its expiration date.
    Get started with Passion+

    Choose a treatment plan
    Most of our patients know that what they need is just a few clicks away. Clients start by choosing a treatment plan that best suits their needs.
    Fill Out Medical Forms
    After choosing a treatment plan, it only takes a moment to fill out a medical history form so our physicians have all of the info needed to get you going.
    Provider Review
    Your order will be evaluated by a practitioner licensed in the state you reside. If they have any further questions they will contact you via email, messaging, or phone.
    Prescription Fulfilment
    One of our partnered, U.S. based, registered pharmacies will dispense and ship the medication straight to your door.
    Frequently Asked Questions about Passion+
    What are common side effects of ED medications?

    Side effects from oxytocin are rare. Potential side effects of oxytocin include:

    • Nausea
    • Vomiting
    • Headache
    • Fast or slow heartbeat
    • Heart arrhythmias
    • Decreased sodium levels
    • Allergic reactions

    Potential side effects from tadalafil include:

    • Headache
    • Dyspepsia
    • Nasopharyngitis
    • Muscle aches
    • Respiratory tract infections
    • Heartburn
    • Flushing or a feeling of warmth
    • Back pain
    • Nausea
    • Diarrhea
    • Cough
    • GERD
    • Extremity pain
    • Abdominal pain

    Potential side effects from PT-141 include:

    • Nausea
    • Redness, pain, irritation, and bumps at the injection sites
    Can I drink grapefruit juice with Passion+?

    Grapefruit and grapefruit juice affect how tadalafil (one of the components of Passion+) is metabolized. Grapefruit juice can decrease the metabolism of tadalafil and increase its level in the blood. Grapefruit will decrease the enzyme CYP3A4, which breaks down tadalafil and releases it in a controlled dosage in your body.

    Grapefruit can take 72 hours to metabolize. Do not consume grapefruit while taking tadalafil.

    Potential side effects of combining grapefruit and tadalafil:

    • Redness
    • Flushing
    • Headache
    • Vision changes
    • Shortness of breath
    • Irregular heartbeat
    Do you need a prescription for ED and sexual health medications?

    Yes, in the United States, compounded medications are only available by prescription. A prescription is required to ensure that you do not have any contraindications for the medications.

    What’s the difference between PT-141 and other ED medications?

    Oral ED medications, such as tadalafil, work by increasing blood flow into the penis. Sexual stimulation is required, then a cascade of chemical reactions occurs. The end result is the relaxation of smooth muscle lining blood vessels and the chambers in the penis. This increases blood flow into the penis.

    PT-141 is a synthetic peptide that binds to and activates the melanocortin receptors in the brain. After binding, it increases sexual arousal.

    How long does it take for Passion+ to work?

    Tadalafil takes 30 to 60 minutes to take effect. The time it takes for PT-141 to have its full effect varies, but it can take minutes to an hour. Passion+ can have effects lasting up to 36 hours.

    Why are tadalafil, PT-141 and oxytocin combined?

    PT-141 acts in the brain to increase sexual desire and improve erectile function. After sexual stimulation, tadalafil increases blood flow into the penis and clitoris to increase arousal and the likelihood of orgasm. Oxytocin increases satisfaction with sexual intimacy. Each of the three drugs has a role in improving sexual satisfaction.

    Do I need a prescription before I buy from Invigor Medical?

    No, Invigor Medical employs doctors licensed in all 50 states, and a medical consultation is included with each medical service. Each patient will receive a valid prescription, which is sent to the pharmacy to be filled.

    How long does it take to get my medication?

    Once you have enrolled for medical services with Invigor Medical, it usually takes 7-14 business days before items arrive at your home. This process includes an online medical consultation, prescription approval, the medication getting filled at the pharmacy, and the medication being sent to your home.

    What is Passion+?

    Oxytocin Promotes Feelings of Connectedness and Intimacy

    Oxytocin is a small six-amino acid peptide that functions as a hormone and signaling molecule. Oxytocin has been called the “love hormone” or “trust hormone” because of its association with relationships, whether romantic or social. Blood oxytocin levels increase during sexual arousal and orgasm and during childbirth. Oxytocin release helps partners connect, whether romantic partners or parents and children.

    Oxytocin levels are increased during physical contact, sexual arousal, and orgasm in both men and women. Oxytocin increases the intensity of orgasm and feelings of commitment after sex. Oxytocin may also be involved in feelings of empathy and a sense of well-being.

    Tadalafil Increases Blood Flow

    Tadalafil (generic for Cialis) is a lower-cost option for Cialis that contains the same active ingredients. It works exactly the same way as the brand-name medication in your body. Tadalafil relaxes smooth muscle, allowing blood vessels to dilate, improving erectile function, and increasing arousal for men and women. Increased blood flow into the penis and clitoris increases arousal and orgasm frequency.

    PT-141 (Bremelanotide) Increases Libido and Sexual Response in Women

    Hypoactive sexual desire disorder is not uncommon. It affects 8.9% of women between the ages of 18 and 44, 12.3% of women between the ages of 45 to 64, and 7.4% of women over the age of 65. Low sexual desire tends to increase with age, but distress associated with the disorder decreases, which means that the condition’s prevalence is consistent across ages. Low sexual desire is linked with lower health-related quality of life, lower overall happiness, and a higher risk of anxiety and depression. 

    Female sexual dysfunction is a constellation of symptoms, including decreased desire, interest, arousal, orgasm, or pain with sex. Two large clinical trials demonstrated PT-141 safety and efficacy. Women using bremelanotide (PT-141) had a statistically significant improved sexual desire. Unlike previous treatment options, bremelanotide does not interact with alcohol.

    PT-141 Treats Low Libido and Erectile Dysfunction in Men

    PT-141 appears to act on melanocortin receptors 3 and 4 in the brain. It enhances sexual arousal and penile erections by releasing dopamine, a neurotransmitter in the brain.

    In a double-blind placebo-controlled study, approximately 80% of men developed an erection satisfactory for intercourse after using PT-141 whether the cause of ED was physical or psychological, and 68% of men reported an increase in sexual desire.

    Clinical trials are underway to further investigate PT-141; early results show that PT-141 is effective for men with diabetes and ED and for men who do not respond well to oral ED medications.

    Here are our sources