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Trimix dosage can vary widely from person to person, and several variables help your doctor determine a good starting point. Most patients start by using around five units of TriMix and then increase the dosage in small increments each time until a hard, sustained erection is achieved.
Most men can inject Trimix up to three times per week, with 24 hours between each injection. Injecting more often than this can cause penile scarring.
Trimix is more effective than Viagra based on the percentage of men who report that their ED is improved. The success rate for Trimix is 80% to 95%. Viagra is around 60% to 70% effective for men with moderate ED.
More men use Viagra than Trimix because taking a pill is easier than doing a penile self-injection. However, men using Trimix report that the injection procedure is nearly painless, and the results are fast and consistent.
Many men, especially those taking medications for heart disease, cannot take Viagra or other medications in that class. For these men and men who want an ED treatment option that is unaffected by diet or alcohol consumption, Trimix is a great option.
The American Urological Association recommends a process of shared decision-making when deciding which treatment option to use for ED.
Men should be offered a full range of treatment options. Some men have medical conditions or are taking medications that keep them from taking ED pills. For these men, ED injections are a highly effective option.
Trimix may not work for all men, including men with the following conditions:
Talk to your healthcare provider if Trimix does not work for you. You may need a dosage change. They may also need to review your injection technique to ensure the medication is being delivered into the corpora cavernosa. Also, check the expiration date on your Trimix and ensure that you are storing it correctly.
Trimix is a combination of three medications that work synergistically to increase blood flow into the penis and produce an erection. The three medications in Trimix are:
Caverject only contains prostaglandin.
Trimix should always be injected following your healthcare provider’s instructions. If Trimix is injected too frequently or at too high a dose, it could cause priapism.
Priapism is an erection that lasts longer than four hours. A prolonged erection allows blood to sit in the penis for too long. Fresh blood is needed to replenish oxygen and nutrients and remove waste products. Untreated priapism can damage the penis.
It is important to follow the instructions provided by your healthcare provider and pharmacist.
In general:
Trimix must be stored refrigerated at 36°F–46°F. Keep Trimix away from light and extreme temperatures. Discard expired medication properly.
Detailed storage instructions are usually included with your Trimix prescription, as they may vary between compounding pharmacies.
Those with a known hypersensitivity to Trimix or any of its components, sickle cell disease, sickle cell trait, multiple myeloma, leukemia, or other blood disorders, a penile implant or prosthesis, penile scarring or anatomical deformities, or a history of priapism should not take Trimix. Don’t take Trimix if you take blood thinners.
Trimix should not be used in conjunction with other ED therapies without consulting with your healthcare provider.
Sometimes, they are used together, but doing so increases the risk of side effects.
Finding your ideal Trimix dose can take a little fine-tuning—that’s completely normal. Everyone responds differently at first, and our goal is to help you get it right safely and affordably.If your provider determines your initial formula is a little too strong or too weak, you may be eligible for an Adjustment Vial—a specially prepared vial designed to help you dial in your optimal dose. The cost is $99 plus shipping within 30 days of your first order. This service exists to make your early experience smoother and more cost-effective, so you can reach your ideal results without paying full price for a new prescription.
Some men need a formulation that’s more customized than the standard Trimix range. If your provider determines that you’d benefit from a stronger, weaker, or more precisely balanced dose, we can coordinate a Custom Trimix Formulation through one of our partner compounding pharmacies that specialize in advanced blends. The Custom Trimix Formulation is $349 plus shipping and is dispensed as a 10 mL vial—double the standard size. It’s designed for patients who need a personalized strength to achieve consistent, reliable results while still keeping treatment accessible and cost-effective. If your provider recommends a custom formulation, our team will guide you through every step to ensure your order is processed quickly and safely.
*Prescription medications available only if prescribed by the healthcare provider after an online consultation. This is a compounded medication.