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Trimix Injection Price Guide

Trimix Injection Price Guide

Trimix is a highly effective treatment for erectile dysfunction.  It is only available with a prescription and is compounded – meaning, it is made from its constituent three medications – by a licensed compounding pharmacy, rather than being mass-produced directly by a drug company.  There are several reasons for this, especially the shelf life and storage requirements for Trimix.  However, this process can have an impact on Trimix injection prices – but not always in the ways one might think, either.

In this guide, we’ll take a look at Trimix injection prices.  Specifically, we’ll look at the factors related to Trimix injection prices, discuss insurance coverage for Trimix, provide some guidance and considerations for buying Trimix injections, and more.  We’ll also offer some examples of Trimix injection prices in terms of individual doses or uses when Trimix is sourced from a quality provider and pharmacy. 

Before we get started, however, it’s worth pointing out that this information is provided for educational purposes only.  It is not a substitute for a consultation with a licensed healthcare provider, nor a substitute for information provided with a prescription for Trimix.  Our goal is to provide patients with the background and other information they need to make an informed decision about their ED treatment options, including Trimix.  Additionally, the prices referenced in this guide are purely as examples and may not reflect the current pricing available from Invigor Medical or other providers.

Background On Trimix

It’s always useful to recap the basics of what Trimix is and how it works before talking in more detail about specific topics like Trimix injection prices.  We’ve discussed these aspects of Trimix in much more detail in separate articles and guides, as well as provide an overview on the main Trimix page on our site.  We encourage you to review all of this information if you have questions about the medication or how it works beyond this simple overview.

In simple terms, Trimix is an injectable medication designed to treat erectile dysfunction.  It comprises three constituent active ingredients – phentolamine, papaverine, and alprostadil – which are all designed to help improve erectile function.  Each works differently, though all three promote the two main mechanisms of male erection – muscle relaxation and blood flow. 

Unlike oral ED treatments, which work systemically in the body, Trimix is injected directly into the penis and works locally to produce an erection.  Most people develop an erection within 5 to 20 minutes following administration, which lasts for one to two hours.  Upwards of 95% of users in studies (and via anecdotal evidence from the decades of Trimix use) see results in erections satisfactory for penetrative sex.  Trimix is only available with a prescription and is considered a second-line treatment for ED – for use only when oral ED treatments have failed.

Trimix Injection Price Guide

When it comes to buying Trimix, there are lots of things to consider – side effects, whether or not it’s right for your needs, and so on.  Another more practical aspect of the purchasing process is considering the Trimix injection price and whether it is worth it to you.  Even knowing the price of a vial of Trimix does not necessarily tell you the price of a single use of the medication, as numerous other factors come into play.  Next, we’ll talk about some of the most important factors related to Trimix injection pricing so that you can make more informed comparison shopping and purchasing decisions.


Every source where you can buy Trimix shots will have their own costs and profit margins, and therefore their own price for a given quantity of Trimix.  This is largely a function of the raw material and labor costs incurred by the compounding pharmacy, which literally mixes the Trimix from the component ingredients and packages it for distribution.  It’s important to choose a reputable provider who uses an FDA-certified pharmacy based in the US.  That will help ensure you are getting the medication to pay for, and that it is pure, legitimate, and not contaminated or unsafe. 

Trimix Injections
Mentioned Product

Trimix Injections

Trimix Injections are used as a second-line treatment when oral ED medications don’t work.

Learn About Trimix Injections

While you may find cheaper Trimix injection prices from overseas or off-shore providers, this is not an area where you want to cut corners to save a little money.  The risks far outweigh the benefits of a slightly lower cost for effectively a vial of unknown and unregulated substances.


Trimix is available in different strengths, formulations, or ratios of constituent medications.  Most providers only offer one standard formulation, but exactly what that is – and how much of each active ingredient it contains – compared to another provider is an open question that is not always easy to determine.  Of course, a stronger formulation, or a higher ratio of higher-cost ingredients to lower-cost ones, will typically result in a higher Trimix injection price.  This is usually most evident if a provider offers more than one ratio or formulation/strength of the product, but it can be hard to find if they only have one.  This makes it a bit difficult to make sure you make an apples-to-apples comparison between multiple providers and their different Trimix injection prices.


The specific dosage of Trimix that you ultimately end up using will play a large role in Trimix injection prices per dose.  Most people are started on a relatively low dosage, and then gradually increase until they find the ideal working dose for them.  This is usually done in consultation with your doctor or prescriber.  Because of this, there is no standard dose amount, and 1 vial of a set volume of medication will give a different number of doses based on the amount needed per dose.

For example, a 5 mL vial of Trimix (or 500 units) will provide only 10 doses to someone taking 50 units per dose.  By contrast, this same amount may last for 25 doses for someone taking only 20 units per dose.  Therefore, the ultimate Trimix injection price for a single injection would be much lower in the latter case than in the former. 

Of course, you need to take the right amount of medication to achieve the desired results. Trying to take less to stretch the medication or get a better Trimix injection price isn’t recommended, as you may not realize the full effect.  That would defeat the purpose of taking Trimix for erectile dysfunction treatment in the first place.  At the same time, you should never take more than prescribed or advised by your doctor or healthcare provider.  Higher doses tend to result in a higher risk of side effects, especially prolonged erections that do not go away on their own and require emergency medical treatment.  Therefore, you should always use the smallest effective dose, not only for safety reasons but for cost reasons. 

Frequency Of Use

How often you need to use Trimix and how often you have sex will determine how long a given Trimix vial lasts for you.  More frequent use means you will go through the medication faster.  While it won’t necessarily change the Trimix injection price directly in and of itself, it may increase or alter your total spending on Trimix in a given period of time. 

Trimix Injection Price Guide

There are also storage considerations, with a limited shelf life of the medication when refrigerated or frozen.  Be sure to follow the instructions provided with the medication in that regard.  You don’t want to order more than you need and end up throwing it away, as that is a sure way to increase your Trimix injection price artificially.

About Insurance Coverage For Trimix

As a compounded medication, most insurance providers do not cover Trimix or reimburse for it.  Therefore, the Trimix injection price paid, whether your prescription is provided by a doctor and licensed pharmacy, does not generally differ significantly based on insurance.  Trimix injections administered by a doctor in a clinical setting may be covered, but that is not the common method of using the medication. 

However, unreimbursed medical expenses can be claimed as a tax deduction each year in the US. This is subject to certain criteria and conditions.  While we cannot provide tax advice, it is worth remembering if you have a limited income or a disproportionate amount of your spending each year is for unreimbursed medical expenses.  That can help defray and offset the Trimix injection price and the amount you spend each year on Trimix. 

Examples Of Trimix Injection Prices

Below, we’ve put all of these factors into play to develop a few examples of specific Trimix injection prices.  Note that, as always, these are merely hypothetical.  They are designed to illustrate the different ways in which one vial of medication may translate into radically different Trimix injection prices for one person versus the next. 

Please note that we’ve omitted any differences in strength or formulation for simple comparison. We are assuming that all of our example patients are purchasing the same ratio/formulation of compounded Trimix.

Vial Size5 mL5 mL10 mL10 mL
SourceCompany XCompany YCompany XCompany Y
Cost per Vial$249$299$349$399
Dosage25 units20 units40 units50 units
Doses per Vial20252520
Cost per Dose$12.45$11.96$13.96$19.95
Shelf Life Open90 days90 days90 days90 days
Use Frequency7/month6/month5/month7/month
WastageNone7 doses10 dosesNone
True Cost/Dose$12.45$16.61$23.27$19.95
Total Cost/Mo.$87.15$99.67$116.33$139.65

Frequently Asked Questions

When Should You Consider Trimix Injections?

Trimix injections are designed to be used as a second-line treatment for erectile dysfunction. They are designed for when men have not had satisfactory results with oral ED medications or other forms of treatment.  It is not a first-line treatment and should only be used if oral ED medications have failed. 

At that point, you should discuss Trimix injections with your doctor or healthcare provider to see if they might be right for you.  Be sure to address any existing medications, health problems, and similar, to ensure there are no contraindications for use, and follow all of the prescribing guidelines for handling, storage, and proper Trimix use.

What Are The Common Side Effects Of Trimix Injections?

Trimix acts locally via injection, and therefore there are few overall systemic side effects.  Most side effects that do occur tend to be mild and associated with the injection itself.  Some slight pain, redness, bruising, or bleeding may occur at the injection site.  This lessens over time in most patients and can be eliminated by following the proper administration instructions and precautions.  Poor hygiene or not using clean needles may result in infection. 

The most significant side effect that you may experience, especially if you increase dosage too quickly or use too much, is a prolonged erection lasting 4 hours or more. This condition is known as priapism.  It is considered an emergency and needs emergency medical care to treat. Otherwise, there can be permanent damage to the penis.  The best pharmacies offering Trimix also provide an option that comes with an “antidote” or reversal medication to treat this kind of side effect if it occurs.

Does Trimix Actually Work?

Trimix has been used for the last several decades.  Between studies and real-world clinical use data, it has been shown that Trimix is extremely effective at treating ED. Specifically, treating ED in men who have not seen satisfactory results with oral ED medications.  Between 80 and 95% of men reported achieving and maintaining erections suitable for penetrative sex. Still, other studies show a larger range of satisfaction, with the lowest levels seen around 50%. Some studies show even 100% satisfaction at the upper end of the spectrum. 

Trimix Injection Price Guide

For Affordable Trimix Injection Prices, Choose Invigor Medical

If you think Trimix might be the right solution for you and want to ensure you get the best Trimix injection prices, service, and convenience, then consider sourcing your Trimix through Invigor Medical.  Your prescription is then transferred to our US-based compounding pharmacy, and your Trimix is sent right to your home.  It’s easy, fast, and affordable. You can rest assured you are getting 100% legitimate and pure medication, made in an FDA-compliant compounding facility in the US. 

Don’t risk your health and well-being with sketchy offshore providers and mystery drugs! Get the proven benefits of, at a price you can afford to purchase Trimix shots, from a company you can trust – Invigor Medical.


While we strive to always provide accurate, current, and safe advice in all of our articles and guides, it’s important to stress that they are no substitute for medical advice from a doctor or healthcare provider.  You should always consult a practicing professional who can diagnose your specific case.  The content we’ve included in this guide is merely meant to be informational and does not constitute medical advice. 

While we strive to always provide accurate, current, and safe advice in all of our articles and guides, it’s important to stress that they are no substitute for medical advice from a doctor or healthcare provider. You should always consult a practicing professional who can diagnose your specific case. The content we’ve included in this guide is merely meant to be informational and does not constitute medical advice.
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Published: Jun 19, 2020


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