Weight Loss

Remarkable Results of Lipotropic Injections

Lipotropic injections are combinations of vitamins and nutrients that are specifically chosen based on their ability to improve fat metabolism and support weight loss efforts. Lipotropes are most effective for people with a vitamin deficiency. Restoring healthy levels of nutrients such as methionine, inositol, choline, and vitamin B12 can help your metabolism work more efficiently and support your weight loss efforts, along with many other potential benefits. Of course, for the best results, you will also need to consume a low-calorie diet and engage in regular physical activity.

Inositol Research Results

Inositol is a naturally occurring sugar alcohol that affects how glucose is metabolized. It also contributes to cellular structure, metabolism, efficient energy consumption and storage, and fat burning.

Inositol seems to improve insulin sensitivity. This makes it easier for your body cells to respond to insulin as it ushers glucose across cell membranes to use it for energy. When this process does not work as well, a condition called insulin resistance, people are at increased risk for type 2 diabetes mellitus and obesity.¹

Inositol also may change the gut microbiota. This may affect how nutrients are absorbed from the gut and metabolized. Limited clinical research is available.¹

Choline Research Results

Choline is an essential amino acid that is required for cell membrane synthesis, healthy liver and muscle function, and the production of acetylcholine, a chemical messenger (neurotransmitter) in the brain involved in mood regulation, memory, and muscle control.²

Humans can synthesize some choline in their bodies, but most must be obtained through diet or supplement use.³ Variations in your genetic code determine your need for choline. Unlike many other nutrients, choline requirements vary between individuals. Only about 10% of U.S. adults currently meet their gender- and life-stage-specific adequate intake (AI) level for choline.²

Choline is essential for transporting fats from the liver. Choline deficiency can lead to fat accumulation in the liver. Excessive fat buildup in the liver not due to excessive alcohol consumption is called nonalcoholic fatty liver disease (NAFLD). Up to 65% of people who are overweight and 90% of people with obesity have NAFLD.⁴

In a study of over 55,000 adults aged 40 to 75 years, people who consumed less choline had an increased risk of NAFLD. The risk of NAFLD was 32% lower for women in the highest quintile of choline consumption than for women in the lowest. The difference in risk for men was 25%.⁵

A small study of 24 female athletes found that choline supplementation led to weight loss (12% decrease, a decrease in body fat percentage (10% decrease), and decreased leptin levels (6% decrease) over one week. The athletes were attempting to rapidly reduce their weight to gain a competitive advantage.⁶

Methionine Research Results

Methionine is one of nine essential amino acids. It acts as an antioxidant and is converted into sulfur-containing molecules that protect body tissues, modify DNA and maintain healthy cellular function. It is used by the body, along with cysteine, to make muscle. Methionine is also converted to homocysteine and SAM, a methyl donor that is involved in many steps in fat metabolism.

Methionine and choline are essential for transporting fat from the liver. Research suggests that people who consume low-methionine and low-choline diets are at increased risk for fatty liver disease (NAFLD), a serious condition that is more common in people with overweight and obesity. Fatty liver disease is associated with obesity, metabolic syndrome, insulin resistance, diabetes, and abnormal blood lipids.⁷

In one study, methionine restriction in people with metabolic syndrome led to a shift to increased fat usage for fuel and a decrease in liver fat. Methionine restriction also reduces blood lipids and improves insulin sensitivity. More research is needed because both the control and experimental groups lost weight. The authors noted that the study withdrawal rate was high because of difficulty finding a palatable low-methionine diet.⁸

More studies are needed to better understand the role of methionine in fat metabolism and weight management.

Vitamin B12 Research Results

Vitamin B12 is a water-soluble vitamin that is essential for cellular growth and reproduction, blood cell formation, healthy nerve function, and DNA and protein synthesis.

Restoring vitamin B12 levels in people with vitamin B12 deficiency boosts energy levels, fights fatigue, and optimizes metabolism. Obesity affects one in three people worldwide, and the World Health Organization is concerned about widespread vitamin B12 and folate deficiencies. Epidemiological studies have shown a link between vitamin B12 and folate deficiencies and increased metabolic risk. Researchers are studying the link between low vitamin B12 and obesity, insulin resistance, type 2 diabetes, and cardiovascular disease.⁹

While results from using lipotropic injections are not well documented in research, there is evidence that lipotropes improve fat metabolism and support weight loss in people with micronutrient deficiencies. Of course, lipotropic injections should be only one part of your weight management plan. Supplements cannot replace the value of a healthy diet and exercise.

Buy B12 Lipotropic injections online.

Disclaimer

While we strive to always provide accurate, current, and safe advice in all of our articles and guides, it’s important to stress that they are no substitute for medical advice from a doctor or healthcare provider. You should always consult a practicing professional who can diagnose your specific case. The content we’ve included in this guide is merely meant to be informational and does not constitute medical advice.

References

1. Caputo M, Bona E, Leone I, Samà MT, Nuzzo A, Ferrero A, Aimaretti G, Marzullo P, Prodam F. Inositols and metabolic disorders: From farm to bedside. J Tradit Complement Med. 2020 Mar 24;10(3):252-259. doi: 10.1016/j.jtcme.2020.03.005. PMID: 32670820; PMCID: PMC7340869.

2. Wallace TC, Blusztajn JK, Caudill MA, Klatt KC, Natker E, Zeisel SH, Zelman KM. Choline: The Underconsumed and Underappreciated Essential Nutrient. Nutr Today. 2018 Nov-Dec;53(6):240-253. doi: 10.1097/NT.0000000000000302. Epub 2018 Nov 13. PMID: 30853718; PMCID: PMC6259877.

3. NIH. (2020).Office of Dietary Supplements – Choline. Retrieved from https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/

4. Zeisel SH, Corbin KD. Choline. In: Erdman JW, Macdonald IA, Zeisel SH, eds. Present Knowledge in Nutrition. 10th ed. Washington, DC: Wiley-Blackwell; 2012:405-18.

5. Yu D, Shu XO, Xiang YB, Li H, Yang G, Gao YT, Zheng W, Zhang X. Higher dietary choline intake is associated with lower risk of nonalcoholic fatty liver in normal-weight Chinese women. J Nutr. 2014 Dec;144(12):2034-40. doi: 10.3945/jn.114.197533. Epub 2014 Oct 15. PMID: 25320186; PMCID: PMC4230213.

6. Elsawy G, Abdelrahman O, Hamza A. Effect of choline supplementation on rapid weight loss and biochemical variables among female taekwondo and judo athletes. J Hum Kinet. 2014 Apr 9;40:77-82. doi: 10.2478/hukin-2014-0009. PMID: 25031675; PMCID: PMC4096089.

7. Chiba T, Suzuki S, Sato Y, Itoh T, Umegaki K. Evaluation of Methionine Content in a High-Fat and Choline-Deficient Diet on Body Weight Gain and the Development of Nonalcoholic Steatohepatitis in Mice. PLoS One. 2016 Oct 10;11(10):e0164191. doi: 10.1371/journal.pone.0164191. PMID: 27723801; PMCID: PMC5056759.

8. Plaisance EP, Greenway FL, Boudreau A, Hill KL, Johnson WD, Krajcik RA, Perrone CE, Orentreich N, Cefalu WT, Gettys TW. Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. J Clin Endocrinol Metab. 2011 May;96(5):E836-40. doi: 10.1210/jc.2010-2493. Epub 2011 Feb 23. PMID: 21346062; PMCID: PMC3085194.

9. Boachie J, Adaikalakoteswari A, Samavat J, Saravanan P. Low Vitamin B12 and Lipid Metabolism: Evidence from Pre-Clinical and Clinical Studies. Nutrients. 2020 Jun 29;12(7):1925. doi: 10.3390/nu12071925. PMID: 32610503; PMCID: PMC7400011.