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Does Online Prescription Weight Loss Medication Work?

Apr 3, 2024
Does Online Prescription Weight Loss Medication Work?

If you are one of the 160 million Americans struggling with obesity, you may have considered taking a newer online weight loss prescription. The online prescription weight loss industry is gaining momentum as people get positive results using safe and effective weight loss products

A growing body of scientific evidence backing the safe and effective use of many of these newer weight loss prescription online products looks favorable. 1 But what are these medications? Do they work? Continue reading this article to learn more about the efficacy and safety of the most popular products available.

Types of Online Prescription Weight Loss Medication

Various popular online weight loss prescription medications are available today. Here are a few of the top products, their benefits, side effects, and recent studies on their safety and effectiveness.


Semaglutide is an online prescription weight loss medication that offers many benefits for people who are overweight or obese. Not only does this product help curb your appetite, semaglutide also helps promote metabolic health, offering benefits such as:

  • Controlling appetite
  • Reducing food cravings 
  • Increasing the feeling of fullness after eating 
  • Promoting weight loss
  • Lowering blood sugar levels
  • Increasing insulin sensitivity (higher insulin sensitivity levels translate to the need for less insulin to lower blood sugar)
  • Lowering the risk of type 2 diabetes
  • Lowering blood pressure
  • Reducing triglycerides and improving cholesterol levels
A woman on an Online Prescription Weight Loss Medication

Side Effects of Semaglutide

Common side effects of semaglutide observed in studies include:

  • Fatigue
  • Headache
  • Dizziness
  • Bloating 
  • Burping
  • Nausea and vomiting
  • Heartburn
  • Diarrhea or constipation
  • Abdominal pain
  • Dizziness
  • Injection site reactions (e.g., itching, redness, pain, or swelling at the site)

Other side effects of semaglutide injections may include an allergic reaction. Contact your healthcare provider if you experience any unusual side effects. 

Infographics Semaglutide

Semaglutide Study

Over 1900 study participants who didn’t have diabetes and had a BMI of 30 or higher, were involved in a 2021 double-blind clinical trial on the safety and effectiveness of semaglutide.3 After taking semaglutide weekly injections for approximately 17 months, the average change in body weight was 14.9%, or around 30 pounds. The study authors concluded, “In participants with overweight or obesity, 2.4 mg of semaglutide once weekly plus lifestyle intervention was associated with sustained, clinically relevant reduction in body weight.”3


Liraglutide is an injectable treatment for type 2 diabetes, obesity, and cardiovascular disease in people with obesity. The benefits of liraglutide include:

  • Promoting weight loss
  • Controlling cravings and hunger
  • Increasing a feeling of fullness after eating
  • Lowering blood sugar
  • Improving good cholesterol levels
  • Increasing insulin sensitivity

Side Effects of Liraglutide

Common side effects of liraglutide include:

Curvy girl standing by the window in a gym
  • Dizziness
  • Heartburn
  • Headache 
  • Fatigue
  • Abdominal pain
  • Nausea and vomiting
  • Diarrhea or constipation
  • Low blood sugar (in people with type 2 diabetes)
  • Injection site reactions (e.g., itching, redness, and swelling)

There may be other side effects associated with liraglutide injection, including the possibility of an allergic reaction.* Call your healthcare provider if you experience any unusual side effects.

Liraglutide Study

Clinical trials have shown that over half of the study participants who took liraglutide lost more than 5% of their body weight, and 10% of the study participants experienced a 10% body weight loss.4 For a 200 lb. person, this equates to a 20 lb. weight loss.

Weightloss - waist measure tape


Taking tirzepatide once a week promotes weight loss and treats type 2 diabetes. Tirzepatide is often prescribed in combination with a healthy diet and exercise regimen. 

Benefits of Tirzepatide

The benefits of tirzepatide include:

  • Decreasing appetite and food cravings
  • Slowing down digestion 
  • Increasing a feeling of fullness
  • Promoting weight loss
  • Increasing insulin levels (for lowering blood sugar)
  • Reducing bad (LDL) cholesterol and triglycerides
  • Reducing liver fat
  • Reducing the risk of heart disease 
  • Promoting bone health by increasing bone density

Tirzepatide Side Effects

The most common side effects that were seen in patients taking tirzepatide include:5

  • Fatigue
  • Indigestion
  • Nausea and vomiting
  • Diarrhea or constipation
  • Hair loss 
  • Gastroesophageal reflux disease (GERD)
  • Injection site reactions (e.g., itching, pain, swelling, or redness)
Two women standing next to each other in workout clothes

Note, that tirzepatide and other GLP-1 agonists have a boxed warning; this is the FDA’s most serious warning about possible side effects of a drug. The warning must be printed on the drug’s label, informing patients of the risk. The boxed warning reads:


GLP-1 agonists have been found in animal studies to cause a type of thyroid tumor called “C-cell tumors.”  This includes medullary thyroid carcinoma (MTC). It’s unknown whether tirzepatide (and other GLP-1 agonists) causes this type of cancer in humans, but due to the potential risk, people with MTC or a family history of MTC should not take tirzepatide. 

Tirzepatide Studies

A 2023 meta-analysis (i.e., a type of study that combines results from several different research sources and identifies trends), discovered that depending on the dose they were taking, patients lost between 8 and 12 percent of their body weight (17-26 pounds) after taking tirzepatide. 7 

Male waist measuring tape

LDN Boost

LDN Boost is an online weight loss prescription that combines several medications, including naltrexone, oxytocin, and vitamin B12, to enhance weight loss while stabilizing your mood. 

Benefits of LDN Boost

The benefits of LDN Boost include:

  • Helps control appetite
  • Reduces food cravings
  • Increases feeling of fullness
  • Boosts fat metabolism
  • Improves energy 

The most common side effects when taking LDN Boost include:

  • Fatigue
  • Confusion
  • Nausea or vomiting
  • Skin rash
  • Upset stomach
  • Headache
  • Painful urination
  • Joint or muscle pain
Does Online Prescription Weight Loss Medication Work?

LDN Boost/Naltrexone Study

A 2020 review study of 191 research articles and 10 studies concluded that in most of these studies, a primary outcome of naltrexone/bupropion, prescribed for obesity, was at least a 5% to 10% weight loss.8  The study authors wrote, in conclusion, our systematic review suggests that naltrexone/bupropion treatment is effective in weight loss amongst overweight subjects. The naltrexone/bupropion treatment was well tolerated by the patients, and side effects were rarely reported.” More research is needed to evaluate the potential weight loss benefits of low-dose naltrexone.

Get Your Weight Loss Prescription Online 

Are you searching for a way to get prescription weight loss prescription online? At Invigor Medical, we are a national wellness clinic that specializes in telehealth services for weight management, supporting longevity, and sexual health. Our licensed physicians offer online consultations, prepackaged along with your weight loss prescription. The process is easy. Simply choose the program you want, fill out the online medical form, consult with the physician, and if you are approved, you’ll receive your prescription in the mail from one of our partnered pharmacies. Start your weight loss program today.

*An allergic reaction could occur when taking online weight loss medication. If you experience hoarseness, trouble breathing, swelling of your hands, mouth, or throat, or any other unusual symptoms, you must seek emergency medical care immediately.

Frequently Asked Questions

Can I get weight loss meds prescribed online?

Yes, you can get weight loss medications prescribed online through telehealth platforms. Many healthcare providers offer virtual consultations and can prescribe weight loss medications after evaluating your medical history and needs.

What is the most effective weight loss prescription drug?

The most effective weight loss prescription drug varies depending on individual factors such as medical history, lifestyle, and preferences. Some commonly prescribed weight loss medications include phentermine, liraglutide, orlistat, and bupropion/naltrexone, but effectiveness can vary from person to person.

How well do prescription weight loss pills work?

Prescription weight loss pills can be effective for some individuals when used as part of a comprehensive weight loss program that includes diet, exercise, and lifestyle changes. However, results may vary, and weight loss medications should be used under the supervision of a healthcare provider.

Can you get weight loss medication by telehealth?

Yes, you can obtain weight loss medication through telehealth services. Many online platforms and healthcare providers offer virtual consultations where prescriptions can be provided based on your medical history and needs. It’s important to ensure that you consult a licensed healthcare provider and follow their guidance when using weight loss medication.

While we strive to always provide accurate, current, and safe advice in all of our articles and guides, it’s important to stress that they are no substitute for medical advice from a doctor or healthcare provider. You should always consult a practicing professional who can diagnose your specific case. The content we’ve included in this guide is merely meant to be informational and does not constitute medical advice.


  • Harvard Health Publishing. Diet and Weight Loss.
  • Medline Plus. (2024) Semaglutide Injection.
  • Wilding JPH, Batterham RL, Calanna S, et al. Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med. 2021;384(11):989-1002. doi: 10.1056/NEJMoa2032183
  • Davies MJ, Bergenstal R, Bode B, Kushner RF, Lewin A, Skjøth TV, Andreasen AH, Jensen CB, DeFronzo RA; NN8022-1922 Study Group. Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial. JAMA. 2015 Aug 18;314(7):687-99. doi: 10.1001/jama.2015.9676. Erratum in: JAMA. 2016 Jan 5;315(1):90.
  • Eli Lilly and Company. ZEPBOUND- tirzepatide injection, solution/.
  • Farzam K, Patel P. Tirzepatide. [Updated 2023 Jul 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from:
  • de Mesquita, Y.L.L., Pera Calvi, I., Reis Marques, I. et al. Efficacy and safety of the dual GIP and GLP-1 receptor agonist tirzepatide for weight loss: a meta-analysis of randomized controlled trials. Int J Obes 47, 883–892 (2023).
  • Kulak-Bejda A, Bejda G, Waszkiewicz N. Safety and efficacy of naltrexone for weight loss in adult patients – a systematic review. Arch Med Sci. 2020 Sep 10;17(4):940-953. doi: 10.5114/aoms.2020.96908


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