Vitamin D3 controls calcium absorption, a mineral essential for bone formation and muscle strength
Vitamin D3 is essential for proper immune function
Low vitamin D3 is linked to depression and other mood disorders
Low vitamin D3 is associated with an increased risk of allergies, asthma, and eczema
Vitamin D3, also known as cholecalciferol, is produced in the skin when it is exposed to sunlight, can be consumed in the diet, and is a hormone naturally produced in the body. Vitamin D3 is a fat-soluble vitamin that helps regulate calcium and phosphate levels in the body. It is important for bone and muscle strength and supports immune function.
In a study of U.S. adults, 39.92 percent of 4962 people surveyed were vitamin D deficient. Another study found that the overall prevalence rate of vitamin D deficiency was 41.6%, with the highest rate in Black Americans at 82.1%, followed by Hispanics at 69.2%.
Vitamin D3 can be synthesized in the body after exposure to UVB rays from the sun. Getting adequate vitamin D from the sun is not as easy as it might sound. UVB rays are filtered by clouds, air pollution, and the amount of atmosphere between you and the sun. When the sun is lower than 45 degrees in the sky or your shadow is longer than you are tall, you will probably not get much UVB exposure.
The following conditions increase the risk of vitamin D3 deficiency:
It is hard to get enough vitamin D3 from the diet alone, especially for people consuming a vegan or vegetarian diet. Decreased UVB exposure can increase the risk of vitamin D3 deficiency.
Vitamin D3 is a hormone produced by the kidneys that controls blood calcium levels and helps regulate the immune system. It easily passes through cell membranes and interacts with DNA to produce proteins. In addition to the immune system, vitamin D3 affects heart function, bone strength, muscle contractility, and brain function.
Ultraviolet B rays from the sun penetrate the skin and convert 7-dehydrocholesterol to vitamin D3 (cholecalciferol), a precursor to the active form of vitamin D. The amount of vitamin D produced in the skin from UV light can vary from the equivalent of 10,000 to 25,000 IU. Vitamin D created by UV light exposure may last twice as long in the blood as vitamin D obtained from food.
Vitamin D3 is converted to 25-hydroxyvitamin D3 (calcidiol) in the liver. Calcidiol is the storage form of the vitamin. It is stored in fat until it is needed.
25 hydroxy-vitamin D is then converted to 1,25 dihydroxy-vitamin D (calcitriol) in the kidney or locally by immune cells. Vitamin 1,25 dihydroxy-vitamin D is the active form of vitamin D.
Receptors for vitamin D are also found on immune cells. Vitamin D can modulate both arms of the immune system: innate and adaptive immunity.
Vitamin D3 is a hormone that is created by exposure to UVB light or consumed in the diet. It goes through several processing steps involving the skin, liver, and kidney. Vitamin D3 has effects throughout the body. Getting enough vitamin D3 has numerous health benefits and may protect against several medical conditions.
The consultation with the practitioner is always included when you buy Vitamin D3.
Our friendly staff are knowledgeable and are readily available to answer any questions.
When you purchase Vitamin D3, all required supplies are always included.
Skip the in person doctor’s visit and consult remotely, and get Vitamin D3 shipped direct.
Our US based, FDA registered pharmacies provide quality meds tested for purity and potency.
Our licensed doctors cover all 50 states and are very well versed with the medications we offer.
Vitamin D3, also known as cholecalciferol, helps your body absorb calcium. Having normal vitamin D, calcium, and phosphate levels is essential for building and maintaining strong bones. Conversely, vitamin D deficiency is linked to osteoporosis, reduced bone density, fragility, and increased risk of falls.
Vitamin D3 also plays a role in immune function and protection against cell damage. Vitamin D deficiency has been linked to an increased risk of common cancers, autoimmune disorders, high blood pressure, and infectious diseases.
Any injectable medication requires a prescription for use, including vitamin D3 injections.
Vitamin D is a fat-soluble vitamin that is stored in the body. Side effects from excess vitamin D are typically due to increased calcium levels. Potential side effects of vitamin D supplements include:
Foods highest in vitamin D are:
Vitamin D deficiency is common. According to the NIH, most people in the U.S. consume less than the recommended amounts of vitamin D.
Groups at highest risk for vitamin D deficiency:
Although vitamin D does not darken skin, there is a link between skin pigmentation and vitamin D levels. Melanin, the pigment that darkens the skin, increases due to UV light exposure. It shields the DNA of epidermal cells from UV rays. Damaged DNA increases the possibility of mutations that lead to skin cancer.
In contrast, too much melanin can interfere with vitamin D production in the skin. Darker pigmented skin was an evolutionary advantage early in human history when everyone lived near the equator because it protected against skin cancer. More melanin was a tradeoff for less vitamin D as people migrated north and south.
According to some studies, there is a direct relationship between skin pigmentation and the skin’s ability to produce vitamin D3. However, others do not reach the same conclusion, suggesting that genetic factors, baseline vitamin D levels, and the duration and dose of UV light influence vitamin D production in the skin.
In December, January, and February, there is almost no vitamin D effective UV radiation at 40 degrees latitude.
At 90 degrees latitude, there is no effective vitamin D radiation for eight months out of the year.
Anyone who lives above the 35th parallel, which runs through the middle of the United States, will not get enough vitamin D during the winter because the sun’s angle with the earth is too great.
Even in the summer, you may be at risk for vitamin D deficiency because, according to a recent survey, Americans spend only 7.6 percent of their time outside.
Vitamin D deficiency is more common in people who are overweight or have obesity. Vitamin D is a fat-soluble vitamin. Increased body fat means more storage for vitamin D. The body needs access to soluble vitamin D.
A study comparing participants at a normal weight to obese and overweight subjects found they had a serum vitamin D level that was 7.9 ng/ml lower and 3.2 ng/ml lower, respectively. It appears that belly fat has the biggest impact on vitamin D levels.
Other confounding variables may be that people who are obese may be less able to move around and get outside and may have an increased incidence of bariatric surgery, leading to malabsorption of fat-soluble vitamins.
The endocrine societies recommend that individuals with obesity be given 2 to 3 times more vitamin D supplementation to correct a deficiency than those of average weight.
There is accumulating evidence suggesting a relationship between vitamin D and obesity. More research is needed to fully understand what the relationship is.