Erectile Dysfunction: Trimix Injections

Trimix

Trimix is a highly effective formulation comprised of three medications — phentolamine, papaverine, and alprostadil — that work synergistically with a 95% success rate. All three medications increase blood flow into the penis, helping men get and sustain an erection. You can buy Trimix from Invigor Medical with an included medical consultation.

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Can I Buy Trimix?

Patients of Invigor Medical can buy Trimix, prescribed by specialists and filled by an FDA-registered pharmacy.

Do we offer Trimix as part of a treatment plan?

Yes

High Success Rate	80-95% success rate
Works Fast	Works within minutes

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How Does Trimix Work?

Three medications work synergistically in Trimix: Papaverine increases cyclic adenosine monophosphate (cAMP) production, which relaxes the smooth muscle in the walls of blood vessels. Its mechanism is not completely understood because it works on many pathways. Ultimately, it increases blood flow into the penis and inhibits outflow resulting in an erection. Phentolamine is an alpha-adrenoceptor antagonist that relaxes and dilates blood vessels entering the penis, thereby increasing blood flow. Alprostadil is a synthetic version of prostaglandin E1. It also dilates blood vessels and increases blood flow into the penis.

Benefits of Trimix

Intracavernosal injections are a safe erectile dysfunction treatment option for a diverse group of men, including men with diabetes and cardiovascular disease.

Very effective combination of medications to treat erectile dysfunction
80-95% effectiveness

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Trimix Treatment Plan

Better Erections

Trimix injections are a highly effective ED treatment option for a diverse group of men, including men with diabetes and cardiovascular d...

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Drug Details

Indications

What is Trimix used for?

Erectile dysfunction

Contraindications

You should avoid Trimix if you are/have:

As with all medications for ED, you should not use Trimix if you have ever been told by a healthcare provider that your heart is not healthy enough for sexual activity. Trimix should not be taken with any oral ED medications.

Trimix and oral ED medications: Do not take sildenafil, vardenafil, or avanafil within 18 hours (before or after) an injection. Do not inject within 72 hours of taking tadalafil 10 mg or 20 mg.

Before using Trimix, advise your healthcare provider if you:

Have a hypersensitivity or an allergy to any component in the formulation.
Have a condition that predisposes you to priapism (a painful erection lasting over four hours)
Have sickle cell anemia, multiple myeloma, or leukemia
Have an anatomical deformity of the penis
Are taking any medications that interfere with blood clotting
Are taking any medications, herbs, nonprescription drugs, or supplements, especially medications for high blood pressure, medications for depression, or those classified as MAO inhibitors such as phenelzine or a sleep aid such as trazadone.

Trimix Side Effects

What are the side effects of Trimix?

Potential side effects of Trimix include the following:

Common Trimix Side Effects

Priapism is an erection that has lasted more than four hours. Untreated priapism can damage the structure of the penis.
Bruising at the injection site may occur depending on injection frequency and technique.
Fibrosis or scarring of the penis may occur, though the risk is thought to be very small.
Pain or redness at the injection site
Lumps, swelling, tenderness, or curvature of the erect penis may occur and are largely dependent on the injection technique.

Rare Trimix Side Effects

Diarrhea
Nausea
Stomach cramps or vomiting
An allergic reaction
A sudden decrease in blood pressure
Increased heart rate or abnormal heart rhythm

Trimix Dosage Information

Trimix Dosage & Frequency

Typical Trimix Dosage & Frequency

0.1 - 0.5mL injection
20-30 Minutes Before Sex

References

https://www.suna.org/sites/default/files/download/members/unjarticles/2006/06dec/449.pdf
https://search.proquest.com/openview/c9c95ac19b1799ba6eb18042c7d52736/1?pq-origsite=gscholar&cbl=32986
https://www.nature.com/articles/3900585.pdf?origin=ppub
https://healthcare.utah.edu/menshealth/conditions/erectile-dysfunction/trimix-injection.php
https://pubmed.ncbi.nlm.nih.gov/30895359/
https://www.mskcc.org/cancer-care/patient-education/penile-injection-therapy
https://www.empowerpharmacy.com/drugs/trimix-injection
https://www.mskcc.org/cancer-care/patient-education/penile-injection-therapy

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