Trimix
Trimix
Trimix
Trimix is a highly effective formulation comprised of three medications — phentolamine, papaverine, and alprostadil — that work synergistically with a 95% success rate. All three medications increase blood flow into the penis, helping men get and sustain an erection. You can buy Trimix from Invigor Medical with an included medical consultation.

How to Get Started on Trimix?

Get Trimix Injections from Invigor Medical
FDA Designation
Category
For Use By
Delivery Method
Included Compounds

Can I Buy Trimix?


Patients of Invigor Medical can Buy Trimix, prescribed by specialists, and filled by an FDA-registered pharmacy.


Do We Offer Trimix as part of a treatment plan?
Yes
High Success Rate
80-95% Success Rate
Works Fast
Works within minutes

How Does Trimix Work?

Three medications work synergistically in Trimix: Papaverine increases cyclic adenosine monophosphate (cAMP) production, which relaxes the smooth muscle in the walls of blood vessels. Its mechanism is not completely understood because it works on many pathways. Ultimately, it increases blood flow into the penis and inhibits outflow resulting in an erection. Phentolamine is an alpha-adrenoceptor antagonist that relaxes and dilates blood vessels entering the penis, therefore, increasing blood flow. Alprostadil is a synthetic version of prostaglandin E1. It also dilates blood vessels and increases blood flow into the penis.

Benefits of Trimix


Intracavernosal injections are a safe ED treatment option for a diverse group of men, including men with diabetes and cardiovascular disease.
  • Very effective combination of medications to treat erectile dysfunction
  • 80-95% Effective Rate

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Where do I Start?

Start by Selecting a Treatment Plan

Drug Details

Indications

What is Trimix used for?

  • Erectile dysfunction

Contraindications

When should you avoid Trimix?

  • As with all medications for ED, you should not use Trimix if you have ever been told by a healthcare provider that your heart is not healthy enough for sexual activity. Trimix should not be taken with any oral ED medications.
  • Before using Trimix, advise your health care provider if you:
  • Have a hypersensitivity or an allergy to any component in the formulation.
  • Have a condition that predisposes you to priapism (a painful erection lasting over 4 hours)
  • Have sickle cell anemia, multiple myeloma, or leukemia
  • Have an anatomical deformity of the penis
  • Are taking any medications that interfere with blood clotting.
  • Are taking any medications, herbs, nonprescription drugs, or supplements, especially medications for high blood pressure, medications for depression, or classified as a MAO inhibitor such as phenelzine or a sleep aid such as Trazadone.
  • Trimix and oral ED medications: Do not take Sildenafil, Vardenafil, or Avanafil within 18 hours (before or after) an injection. Do not inject within 72 hours of taking tadalafil 10 mg or 20 mg.
Trimix Side Effects

What are the side effects of Trimix?

Potential side effects of Trimix include the following:
Common Trimix Side Effects
  • Priapism is an erection that has lasted more than four hours. Untreated priapism can damage the structure of the penis.
  • Bruising at the injection site may occur depending on injection frequency and technique.
  • Fibrosis or scarring of the penis may occur, though the risk is thought to be very small.
  • Pain or redness at the injection site
  • Lumps, swelling, tenderness, or curvature of the erect penis may occur and are largely dependent on the injection technique.
Rare Trimix Side Effects
  • Diarrhea
  • Nausea
  • Stomach cramps or vomiting
  • An allergic reaction
  • A sudden decrease in blood pressure
  • Increased heart rate or abnormal heart rhythm.

Trimix Dosage Information

Trimix Dosage & Frequency

Typical Trimix Dosage & Frequency
  • 0.1 - 0.5mL injection
  • 20-30 Minutes Before Sex

References

  • https://www.suna.org/sites/default/files/download/members/unjarticles/2006/06dec/449.pdf
  • https://search.proquest.com/openview/c9c95ac19b1799ba6eb18042c7d52736/1?pq-origsite=gscholar&cbl=32986
  • https://www.nature.com/articles/3900585.pdf?origin=ppub
  • https://healthcare.utah.edu/menshealth/conditions/erectile-dysfunction/trimix-injection.php
  • https://pubmed.ncbi.nlm.nih.gov/30895359/
  • https://www.mskcc.org/cancer-care/patient-education/penile-injection-therapy
  • https://www.empowerpharmacy.com/drugs/trimix-injection
  • https://www.mskcc.org/cancer-care/patient-education/penile-injection-therapy

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