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PT-141
PT-141
PT-141, or Bremelanotide, is a peptide used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. It is also used to increase sex drive and support erections in men.
You can buy PT-141 with an included prescription consultation.
Category
For Use By
Delivery Method

Can I Buy PT-141?


Approved patients can buy PT-141 (Bremelanotide). After consulting with the doctor via an online Telewellness visit and being approved, the pharmacy sends the medication straight to your door.


Do we offer PT-141 as part of a treatment plan?
Yes
Improves Libido
In both men and women
Improves ED
Helps erectile function

How Does PT-141 Work?

PT-141 Influences Sexual Behavior

PT-141 is a nonselective agonist of the melanocortin receptors, which means that it binds to these receptors and induces a similar effect. In the brain, PT-141 influences sexual behavior. How exactly it works is currently unknown. One theory is that it stimulates dopamine release from the medial preoptic area in the brain, an area of the brain associated with sexual behavior.

Additionally, PT-141 is thought to work through the central nervous system rather than directly on the vascular system. This sets it apart from other sexual dysfunction treatments that primarily target the vascular system. By potentially affecting the neural pathways involved in sexual arousal, PT-141 offers a unique approach to enhancing sexual response.

Its mechanism also suggests that PT-141 could be effective in treating sexual arousal disorders, which are often rooted in neurological factors. This potential makes PT-141 a promising option for those seeking a treatment that addresses the underlying neurological aspects of sexual function, offering a path to improved intimacy and sexual satisfaction.

Benefits of PT-141


PT-141 (bremelanotide) has the following potential benefits:
  • PT-141
    Improves libido in men
  • PT-141
    Improves the ability to generate and maintain an erection
  • PT-141
    Improves libido in women

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Where Do I Start?

Start by Selecting a Treatment Plan

Drug Details

Indications

What is PT-141 used for?

Indications for PT-141 (bremelanotide) include:
  • Decreased libido in men
  • Erectile dysfunction in men
  • Hypoactive sexual desire in premenopausal women

Contraindications

You should avoid PT-141 if you are/have:

Contraindications for using PT-141 (bremelanotide) include:
  • Heart disease that makes sexual intercourse unsafe
  • Allergies to any component of bremelanotide
  • If you are currently taking naltrexone
  • Uncontrolled high blood pressure
  • Severe kidney or liver disease
PT-141 Side Effects

What are the side effects of PT-141?

Bremelanotide can cause the following side effects:
Common PT-141 Side Effects
  • Nausea, which may be severe, and vomiting.
  • Redness, pain, irritation, and bumps at the injection sites
Rare PT-141 Side Effects
  • Blurred vision
  • Dizziness
  • Headache
  • Nervousness
  • Pounding in the ears
  • Flushing, cough
  • Stuffy nose
  • Tiredness
  • Tingling feeling in fingers and toes
  • Slower or faster heartbeat
  • May darken the color of your gums or skin

References

  • Bremelanotide Injection for Subcutaneous Use
    https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210557s000lbl.pdf
  • Approaches to Treating Female Sexual Interest and Arousal Disorder
    https://go.drugbank.com/articles/A179692
  • Expert Opinion on Existing and Developing Drugs to Treat Female Sexual Dysfunction.
    https://go.drugbank.com/articles/A179689
  • Phase I Randomized Placebo-controlled, Double-blind Study of the Safety and Tolerability of Bremelanotide Coadministered With Ethanol in Healthy Male and Female Participants.
    https://go.drugbank.com/articles/A179686
  • PT-141: A Melanocortin Agonist for the Treatment of Sexual Dysfunction
    https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1749-6632.2003.tb03167.x?sid=nlm%3Apubmed
  • FDA Approves New Drug for Women with Low Sexual Desire Disorder
    https://www.cnn.com/2019/06/21/health/women-sexual-desire-drug-bremelanotide-vyleesi-bn/index.html
  • The Future is Today: Emerging Drugs for the Treatment of Erectile Dysfunction
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163612/
  • Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder
    https://journals.lww.com/greenjournal/pages/articleviewer.aspx?year=2019&issue=11000&article=00002&type=Fulltext

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