PT-141

Bremelanotide, or PT-141, is a peptide used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. It is also used to increase sex drive and support erections in men.

You can buy PT-141 with an included prescription consultation.

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Can I Buy PT-141?

Approved patients can buy bremelanotide (PT-141). After consulting with the doctor via an online Telewellness visit and being approved, the pharmacy sends the medication straight to your door.

Do we offer PT-141 as part of a treatment plan?

Yes

Improves Libido	In both men and women
Improves ED	Helps erectile function

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How Does PT-141 Work?

PT-141 Influences Sexual Behavior

PT-141 is a nonselective agonist of the melanocortin receptors, which means that it binds to these receptors and induces a similar effect. In the brain, PT-141 influences sexual behavior. How exactly it works is currently unknown. One theory is that it stimulates dopamine release from the medial preoptic area in the brain, an area of the brain associated with sexual behavior.

Benefits of PT-141

PT-141 (bremelanotide) has the following potential benefits:

Improves libido in men
Improves the ability to generate and maintain an erection
Improves libido in women

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Where Do I Start?

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PT-141 Treatment Plan

Increased Libido, Increased Sexual Arousal

PT-141 is a melanocortin receptor agonist that is FDA-approved to treat female sexual desire disorder, a cluster of symptoms that affects...

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Drug Details

Indications

What is PT-141 used for?

Indications for PT-141 (bremelanotide) include:

Decreased libido in men
Erectile dysfunction in men
Hypoactive sexual desire in premenopausal women

Contraindications

You should avoid PT-141 if you are/have:

Contraindications for using PT-141 (bremelanotide) include:

Heart disease that makes sexual intercourse unsafe
Allergies to any component of bremelanotide
If you are currently taking naltrexone
Uncontrolled high blood pressure
Severe kidney or liver disease

PT-141 Side Effects

What are the side effects of PT-141?

Bremelanotide can cause the following side effects:

Common PT-141 Side Effects

Nausea, which may be severe, and vomiting.
Redness, pain, irritation, and bumps at the injection sites

Rare PT-141 Side Effects

Blurred vision
Dizziness
Headache
Nervousness
Pounding in the ears
Flushing, cough
Stuffy nose
Tiredness
Tingling feeling in fingers and toes
Slower or faster heartbeat
May darken the color of your gums or skin

References

Bremelanotide Injection for Subcutaneous Use
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210557s000lbl.pdf
Approaches to Treating Female Sexual Interest and Arousal Disorder
https://go.drugbank.com/articles/A179692
Expert Opinion on Existing and Developing Drugs to Treat Female Sexual Dysfunction.
https://go.drugbank.com/articles/A179689
Phase I Randomized Placebo-controlled, Double-blind Study of the Safety and Tolerability of Bremelanotide Coadministered With Ethanol in Healthy Male and Female Participants.
https://go.drugbank.com/articles/A179686
PT-141: A Melanocortin Agonist for the Treatment of Sexual Dysfunction
https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1749-6632.2003.tb03167.x?sid=nlm%3Apubmed
FDA Approves New Drug for Women with Low Sexual Desire Disorder
https://www.cnn.com/2019/06/21/health/women-sexual-desire-drug-bremelanotide-vyleesi-bn/index.html
The Future is Today: Emerging Drugs for the Treatment of Erectile Dysfunction
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163612/
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder
https://journals.lww.com/greenjournal/pages/articleviewer.aspx?year=2019&issue=11000&article=00002&type=Fulltext

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