Naltrexone is used to treat opioid and alcohol abuse in higher doses and is used off-label to treat pain and inflammation in lower doses. Used alone for weight loss, researchers have come to inconsistent conclusions about its efficacy as an appetite suppressant. Low-dose naltrexone supports immune function and increases endorphin release.

Can I buy Naltrexone for for appetite reduction from Invigor Medical?

Patients can buy Naltrexone for for appetite reduction with an included prescription consultation with a doctor.
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Can I Buy Naltrexone?

If you would like to purchase Naltrexone for appetite reduction, learn about Bella+. This capsule supplements a reduced-calorie diet and exercise plan for a powerful weight management plan.

Do we offer Naltrexone as part of a treatment plan?
Modulate Hunger
Appetite reduction especially for people with other chronic disease
Reduce Pain
Increases the release of endorphins which reduce pain and inflammation
Improve Mood
Endorphin release can improve mood and reduce anxiety

How Does Naltrexone Work?

Reduce Cravings and Hunger

Naltrexone is an opiate antagonist. Bupropion is a noradrenergic/dopaminergic antidepressant. Bupropion and naltrexone work together in the hypothalamus to reduce cravings and hunger. They activate POMC neurons in the hypothalamus, a brain region that produces a neurotransmitter that decreases the desire to eat. In the mesolimbic area of the brain, a reward center in the brain that is stimulated by pleasurable activities such as eating, bupropion, and naltrexone can regulate these feelings of pleasure, reducing cravings to eat.

In three studies that enrolled over 4000 participants who were overweight or obese and who also had high lipid levels or high blood pressure, in all studies participants taking naltrexone and bupropion combined with a diet and exercise program lost more weight than those who were taking a placebo with the diet and exercise program. The most common side effects were nausea, constipation, and headache.

Benefits of Naltrexone

Low-dose Naltrexone potential benefits include:
  • Appetite reduction
  • Decreased inflammation
  • Improve Mood
  • Reduce Anxiety
  • Pain relief

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Drug Details


What is Naltrexone used for?

  • Fibromyalgia
  • Chronic fatigue syndrome
  • Autoimmune diseases
  • Ulcerative colitis
  • Crohn’s disease


When should you avoid Naltrexone?

  • Have uncontrolled high blood pressure
  • Seizures
  • Eating disorders
  • Opioid addiction
  • Pregnancy
  • Liver Failure
  • Kidney Failure
Naltrexone Side Effects

What are the side effects of Naltrexone?

Potential side effects from naltrexone:
Common Naltrexone Side Effects
  • Skin rash
  • Stomach Ache
  • Headache
  • Joint or muscle pain
  • Nausea or vomiting
  • Fatigue
  • Chest pain or pounding heartbeat
  • Pain with urination
  • Confusion
  • Itching
  • Depression
  • Ringing in the ears
  • Shortness of breath
Rare Naltrexone Side Effects
  • Hallucinations


  • Naltrexone (
  • Naltrexone (Medline Plus)
  • Naltrexone (NIH)
  • The Use of Low-Dose Naltrexone (LDN) as a Novel Anti-Inflammatory Treatment for Chronic Pain
  • Safety and Efficacy of Naltrexone for Weight Loss in Adult Patients – A Systematic Review

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