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Metformin
Metformin
Metformin
Metformin, a trusted medication for treating type 2 diabetes and polycystic ovary syndrome, goes beyond its primary indications. With the added benefit of weight loss as a known side effect, Metformin offers a potential solution for those seeking to shed pounds, while also addressing metabolic complications and improving overall health.

Can I buy Metformin online?

You can buy Metformin after enrolling as a patient.
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For Use By

Can I Buy Metformin?


Patients can buy Metformin as part of a specialized treatment plan. After a phone call from a treatment specialist, you will be enrolled as a patient, and the pharmacy will ship the medication straight to your door.


Do we offer Metformin as part of a treatment plan?
No
Weight Management
Effective weight loss with Metformin
Metabolic Support
Boost your metabolism with Metformin
Blood Sugar Control
Manage blood sugar levels

How Does Metformin Work?

Metformin: A Treatment for Type 2 Diabetes and Polycystic Ovary Syndrome

Metformin is used to treat type 2 diabetes and insulin resistance in polycystic ovary syndrome. It was FDA-approved for weight loss almost thirty years ago. Weight loss is a known side-effect. How metformin causes weight loss is not fully understood, but it may involve changes in the appetite centers in the brain, a decrease in food intake, decreased glucose production in the liver, or improved insulin sensitivity. Weight loss is likely due to decreased caloric intake rather than increased energy expenditure. Weight loss in metformin studies varies from 6 pounds to 13 pounds (+/- 15 pounds).

Metformin’s Role in Weight Loss: A Known Side Effect

Because the weight loss associated with metformin is modest and inconsistent, the FDA has not approved it as a weight-loss agent, but it continues to be used off-label. The 2015 Endocrine Society Practice Guideline on Pharmacology for Obesity does not recommend the use of metformin as monotherapy for obese patients without metabolic complications such as diabetes. The 2016 AACE/ACE guidelines on obesity management recommend the use of metformin in patients with obesity and evidence of prediabetes or insulin intolerance that does not respond to lifestyle medications or other anti-obesity medications. 

Metformin is also being investigated as an anti-aging medication.

Benefits of Metformin


Metformin provides the following potential benefits:
  • Improves blood glucose control
  • Weight loss

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Drug Details

Indications

What is Metformin used for?

The indications for Metformin include:
  • Treating polycystic ovary syndrome
  • Treating type 2 diabetes

Contraindications

You should avoid Metformin if you are/have:

Contraindications for prescribing Metformin include:
  • Severe kidney disease
  • Metabolic acidosis
  • Diabetic ketoacidosis
  • Known hypersensitivity to metformin hydrochloride
Metformin Side Effects

What are the side effects of Metformin?

Potential side effects of taking Metformin include
Common Metformin Side Effects
  • Decreased vitamin B12 levels
  • Hypoglycemia with decreased calorie consumption or increased exercise
  • Diarrhea
  • Nausea
  • Vomiting
  • Flatulence
  • Astenia
  • Indigestion
  • Abdominal discomfort
  • Headache
Rare Metformin Side Effects
  • None

Metformin Dosage Information

Metformin Dosage & Frequency

Typical Metformin Dosage & Frequency
  • 500 mg or 850 mg
  • Once or twice daily

References

  • Effectiveness of metformin on weight loss in non-diabetic individuals with obesity
    https://pubmed.ncbi.nlm.nih.gov/23147210/
  • Metformin Information
    https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/metformin-information
  • Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
    https://pubmed.ncbi.nlm.nih.gov/17145742/
  • Metformin: Mechanisms in Human Obesity and Weight Loss
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520185/
  • Pharmacological management of obesity: an endocrine Society clinical practice guideline
    https://pubmed.ncbi.nlm.nih.gov/25590212/
  • AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY
    https://pubmed.ncbi.nlm.nih.gov/27219496/
  • GLUCOPHAGE┬« (metformin hydrochloride) Tablets
    https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf

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