Approved patients can buy Metformin Synergy with the included prescription consultation. After consulting with the doctor via an online Telewellness visit, and after the patient is approved, the medication is sent directly from the pharmacy.
Do We Offer Metformin Synergy as part of a treatment plan?
Increase Insulin Sensitivity and improves glucose utilization
Metformin can help decrease appetite and cravings
Reduce fatigue with B12
Metformin is used to decrease blood glucose and fat deposition in the liver and is used to treat type 2 diabetes. Researchers found that combining leucine, metformin and sildenafil worked better than metformin alone at activating the 5′ adenosine monophosphate-activated protein kinase (AMPK)/Sirtuin 1 (Sirt1) pathway which regulates glucose and fat metabolism in the liver. The combination also increases liver energy metabolism and decreases inflammation. Leucine is a direct Sirt1 activator. Sildenafil inhibits phosphodiesterase 5 which increases nitric acid and increases blood flow. This pathway also interacts with the sirtuin pathway as it stimulates Sirt1.
B12 is important in the formation of red blood cells and in regulating gene activity. It is also used to produce myelin, the fatty insulator that surrounds nerve cells that speeds up nerve signaling throughout the body. Obesity, insulin resistance, dyslipidemia, and cardiovascular disease have all been linked to low B12 levels, according to researchers. B12 is involved in the regulation of DNA coding for proteins (epigenetics) as well as many metabolic processes in the cell. There is mounting evidence that B12-DNA interactions regulate lipid metabolism and play a role in fat deposition.