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Topiramate
Topiramate is an antiepileptic medication. It was approved by the FDA to treat seizures in 1996 and migraines in 2004. It is used off-label to treat several medical conditions, including mood, eating, and substance use disorders. In clinical trials, topiramate induced weight loss and improved blood sugar control in adults with type 2 diabetes and obesity. Some users report that topiramate altered their sense of taste, which may help with appetite control. In one study, participants taking topiramate lost an average of 9.1% of their body weight compared to those in the control group who lost 1.7% of their body weight.
Patients can buy Topiramate for appetite reduction with an included prescription consultation with a doctor.
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Can I Buy Topiramate?


If you would like to purchase Topiramate for appetite reduction, learn about Bella+. This capsule supplements a reduced-calorie diet and exercise plan for a powerful weight management plan.


Do we offer Topiramate as part of a treatment plan?
Yes
Lose Weight
Support weight loss efforts
Reduce Migraines
Reduce the incidence of migraines and seizures

How Does Topiramate Work?

Helps with Weight Loss

Topiramate’s exact mechanism of action is not known. It blocks voltage-gated sodium channels in the brain and enhances GABA receptor activity. Both effects exert an inhibitory effect on nerves, which slows the brain’s ability to send electrical signals and explains its efficacy in treating seizure disorders. It also seems to block calcium channels, which may also explain its antiepileptic properties. In animal studies, topiramate was found to cause weight loss and improve insulin sensitivity.

Benefits of Topiramate


Topiramate may have the following potential benefits:
  • Reduce the incidence of migraines and seizures
  • Support weight loss efforts

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Drug Details

Indications

What is Topiramate used for?

  • Alcohol dependency
  • Depression
  • Post-traumatic stress disorder
  • Tourette syndrome
  • Bipolar disorder
  • Eating disorders

Contraindications

You should avoid Topiramate if you are/have:

  • Have glaucoma or eye problems
  • Have metabolic acidosis
  • Have kidney disease
  • Have lung disease
  • Have mood disorders, depression, suicidal thoughts or actions
  • Have liver disease
  • Have a growth disorder
  • Have osteoporosis or osteomalacia
  • Are pregnant or breastfeeding
Topiramate Side Effects

What are the side effects of Topiramate?

Topiramate may cause:
Common Topiramate Side Effects
  • Cold symptoms
  • Fever
  • Appetite loss
  • Stomach pain
  • Diarrhea
  • Nausea
  • Nervousness
  • Drowsiness
  • Dizziness
  • Changes in the sense of taste
  • Numbness and tingling in arms or legs
  • Abnormal vision
Rare Topiramate Side Effects
  • Vision problems that may be permanent if not rapidly treated
  • Birth defects
  • Life-threatening dehydration due to increased body temperature and decreased sweating
  • Increased blood lactic acid levels
  • Suicidal ideation
  • Potentially serious skin rashes
  • Confusion and problems thinking
  • Kidney stones
  • Problems with speech or memory

Topiramate Dosage Information

Topiramate Dosage & Frequency

Typical Topiramate Dosage & Frequency
  • Individualized Dosage
  • As Needed

References

  • https://www.drugs.com/mtm/topiramate.html#side-effects
    https://www.drugs.com/mtm/topiramate.html#side-effects
  • https://medlineplus.gov/druginfo/meds/a697012.html
    https://medlineplus.gov/druginfo/meds/a697012.html
  • https://www.ncbi.nlm.nih.gov/books/NBK554530/
    https://www.ncbi.nlm.nih.gov/books/NBK554530/
  • https://link.springer.com/chapter/10.1007%2F978-3-642-24716-3_20
    https://link.springer.com/chapter/10.1007%2F978-3-642-24716-3_20
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC181115/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC181115/
  • https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-789X.2010.00846.x
    https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-789X.2010.00846.x
  • https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-789X.2010.00846.x
    https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-789X.2010.00846.x
  • https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=21628112-0c47-11df-95b3-498d55d89593
    https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=21628112-0c47-11df-95b3-498d55d89593
  • https://pubmed.ncbi.nlm.nih.gov/11054603/
    https://pubmed.ncbi.nlm.nih.gov/11054603/

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