Phentolamine

Phentolamine is an alpha-adrenergic antagonist that relaxes the smooth muscle lining the corpora cavernosa. It is typically used with papaverine to treat ED. Clinical studies show that phentolamine in combination with papaverine dilate blood vessels entering the penis, with an erection occurring within 20 to 30 minutes.

Can I purchase Phentolamine Shots Online?

Find out where to buy Phentolamine injections.

Learn More

Get Started

Clinical Formula

C₁₇H₁₉N₃O

FDA Designation

Approved

Other Names

OraVerse, Regitine

Can I Buy Phentolamine?

Patients who qualify can purchase Phentolamine in the Bimix, Trimix, or Quadmix formulations for the treatment of Erectile Dysfunction.

Do We Offer Phentolamine as part of a treatment plan?

Yes

Success Rate	80-95% Success
Fast Acting	Works Within Minutes

View Treatment Options

Get Started On Phentolamine

How Does Phentolamine Work?

Phentolamine causes muscle relaxation and a widening of blood vessels

Phentolamine is an alpha-adrenoceptor antagonist, which means that it blocks chemicals that bind to alpha-adrenergic receptors. Competitively binding to their receptors, phentolamine causes muscle relaxation and a widening of blood vessels. When blood vessels are widened, blood pressure decreases, and blood flow into the penis increases. Phentolamine also blocks 5-HT receptors, which cause the release of histamine from mast cells.

Benefits of Phentolamine

Used in combination with other vasodilators to treat erectile dysfunction.

Used in combination with other vasodilators to treat erectile dysfunction.
80-95% Success Rate with Papaverine

Want us to contact you?

Submit your info and we will contact you

Where do I Start?

Start by Selecting a Treatment Plan

Drug Details

Indications

What is Phentolamine used for?

Diagnosing a pheochromocytoma
Treat hypertensive crisis (extremely high blood pressure)
Treat ED (with papaverine)

Contraindications

When should you avoid Phentolamine?

Heart attack or a history of a heart attack
Angina
Known hypersensitivity or allergy to phentolamine

Phentolamine Side Effects

What are the side effects of Phentolamine?

Potential side effects to using phentolamine include:

Common Phentolamine Side Effects

Bruising or bleeding at the injection site
Burning along the penis
Swelling
Difficulty with ejaculation
Dizziness
Prolonged erection (priapism)
Lumps in the penis

Rare Phentolamine Side Effects

Phentolamine Dosage Information

Phentolamine Dosage & Frequency

Typical Phentolamine Dosage & Frequency

Customized Per Individual
As Needed

References

https://pubmed.ncbi.nlm.nih.gov/11402586/
https://go.drugbank.com/drugs/DB00692
https://pubmed.ncbi.nlm.nih.gov/3712604/
https://books.google.com/books?id=EpifDwAAQBAJ&pg=PA160&lpg=PA160&dq=Juenemann,+K.P.,+et+al.,+Hemodynamics+of+papaverine-+and+phentolamine-induced+penile+erection.+J+Urol,+1986.+136(1):+p.+158-61.&source=bl&ots=M4M8288rxw&sig=ACfU3U1Azfgp9dJYM-ezCDR9eFgUQH678Q&hl=en&sa=X&ved=2ahUKEwiyoO-K2NL1AhXxmuAKHfyHBlQQ6AF6BAgCEAM
https://www.drugs.com/sfx/phentolamine-side-effects.html

Some articles that might shed some light on this treatment plan

Everything You Need to Know About Trimix Injections

September 22, 2019

This article will serve as a guide to frequently asked questions about Trimix injections. It will cover basic information such as what Trimix is and what it is used to treat for curious but casual...

Trimix Dosage: How Many Units of Trimix Should I Take?

June 20, 2020

The erectile dysfunction medication Trimix has been shown, time and time again, to be an effective remedy for men who haven’t had success with oral ED treatments. It is available by prescrip...

Trimix Cost: Are They Expensive?

June 21, 2020

One of the most frequently asked questions on the Internet today regarding the erectile dysfunction medication Trimix is, “How much does Trimix cost?” It’s a reasonable question – after all,...