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Papaverine was one of the first injectable medications used to treat erectile dysfunction. It is a vasodilator, which means that it expands blood vessels and increases blood flow into the penis. When papaverine is injected into the intracavernosal space in the penis, it increases blood flow, resulting in an erection. Papaverine is no longer used alone to treat ED. It is used in combination with Phentolamine and Prostaglandin to give better treatment results with fewer side effects. Papaverine is one of four medications that compose a class of injectable erectile dysfunction medications often called Bimix, Trimix, or Quadmix. Most patients who suffer from erectile dysfunction buy Papaverine as part of the Trimix compound.
Get information about how to get Papaverine or Trimix injections.
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Delivery Method

Can I Buy Papaverine?

If you would like to purchase Papaverine for erectile dysfunction, learn about Bimix, Trimix, and Quadmix. These penile injections are 80-95% effective for treating ED.

Do we offer Papaverine as part of a treatment plan?
Success Rate
80-95% success rate
Fast Acting
Works in minutes

How Does Papaverine Work?

Papaverine Relaxes Blood Vessels Entering the Penis

Papaverine increases cAMP levels in the body, which relaxes smooth muscle in the penis and the blood vessels entering the penis. The exact mechanism of action for papaverine is not known. Clinical trials have evaluated its effectiveness in treating ED.

Benefits of Papaverine

Used in combination with other vasodilators to treat erectile dysfunction.
  • Papaverine
    Treats Erectile Dysfunction
  • Papaverine
    Works Rapidly
  • Papaverine
    80-95% Success Rate

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Drug Details


What is Papaverine used for?

Papaverine is used to treat conditions in which smooth muscle spasms such as:
  • Chest pain
  • Circulation problems
  • Heart attacks
  • Stomach or gallbladder disorders


You should avoid Papaverine if you are/have:

  • Heart disease
  • High blood pressure
  • Glaucoma
  • Liver disease
  • Pregnant
Papaverine Side Effects

What are the side effects of Papaverine?

Potential side effects of Papaverine include:
Common Papaverine Side Effects
  • Flushing (feeling of warmth)
  • Sweating
  • Headache
  • Tiredness
  • Dizziness
  • Skin rash
  • Upset stomach
  • Penile pain
  • Diarrhea
  • Constipation
  • Stomach pain
  • Irregular heartbeat
Rare Papaverine Side Effects
  • None

Papaverine Dosage Information

Papaverine Dosage & Frequency

Typical Papaverine Dosage & Frequency
  • Individualized Dosage
  • As Needed



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