Is Bupropion Good for Weight Loss?

Bupropion

Bupropion is an antidepressant that is used off-label for weight loss. Its mechanism of action is not fully understood. It appears to affect monoamine uptake and inhibit the uptake of norepinephrine and dopamine. In a controlled clinical study, 200 patients taking bupropion lost an average of 9.7 pounds (nearly 5% of body weight). Bupropion seems to work in the hypothalamus, where it reduces cravings by activating POMC neurons, and in the mesolimbic area of the brain, which is a reward center stimulated by pleasurable activities like eating.

Patients can purchase Bupropion for weight loss with an included prescription consultation with a doctor.

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Can I Buy Bupropion?

If you would like to purchase Bupropion for weight loss, learn about Bella+. This capsule supplements a reduced-calorie diet and exercise plan for a powerful weight management plan.

Do we offer Bupropion as part of a treatment plan?

Yes

Reduce Cravings

Modulate your brain’s reward center’s response

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How Does Bupropion Work?

Suppress Appetite

Bupropion does not affect serotonin levels, unlike other antidepressants, which means it lacks common side effects associated with antidepressants such as sexual dysfunction, weight gain, and sedation. Its structure closely resembles that of diethylpropion, an appetite suppressant and sympathomimetic agent.

Bupropion is an antidepressant that seems to affect monoamine uptake, antagonize nicotinic receptors, and inhibit the uptake of norepinephrine and dopamine. It appears to affect monoamine uptake and inhibits the uptake of norepinephrine and dopamine. Inhibiting the reuptake of norepinephrine and dopamine may explain how bupropion acts in the brain. Bupropion affects dopamine and norepinephrine concentrations in both the nucleus accumbens and the prefrontal cortex of the brain.

Benefits of Bupropion

Potential benefits of bupropion:

Improve mood
Suppress appetite
Increase energy

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Start by Selecting a Treatment Plan

Bella Treatment Plan

Decreased Body Fat, More Energy

Bella is a combination of six drugs that function in different ways to minimize cravings and suppress appetite, making it easier to contr...

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Drug Details

Indications

What is Bupropion used for?

Bupropion is medically indicated to treat:

Depression
Seasonal affective disorder
Smoking cessation
It is used off-label to treat antidepressant-induced sexual dysfunction
Attention-deficit hyperactivity disorder
Depression associated with bipolar disorder
Obesity

Contraindications

You should avoid Bupropion if you are/have:

Have an allergy to any of its components
Have a seizure disorder
Have recently stopped using alcohol or sedatives
Have arteriovenous malformations
Have had a severe head injury
Have had a severe stroke
Have had a brain tumor
Have a significant central nervous system disease
Are taking monoamine oxidase inhibitors, linezolid, or methylene blue
Have a history of suicidal ideation

Bupropion Side Effects

What are the side effects of Bupropion?

Bupropion carries a black box warning for its potential to cause suicidal ideation in young adults taking this medication. Some potential side effects from bupropion:

Common Bupropion Side Effects

Drowsiness
Anxiety
Excitement
Difficulty falling asleep or staying asleep
Dry mouth
Excessive sweating
Ringing in the ears
Changes in your sense of taste
Frequent urination
Dizziness
Headache
Nausea
Vomiting
Stomach pain
Uncontrollable shaking of a part of the body
Loss of appetite
Weight loss
Constipation
Sore throat

Rare Bupropion Side Effects

Thoughts of suicide or dying
Attempts to commit suicide
New or worsening depression
New or worsening anxiety
An extreme increase in activity and talking (mania)
Other unusual changes in mood or behavior
Trouble sleeping (insomnia)
Elevated blood pressure
Feeling agitated or restless
Panic attacks
New or worse irritability
Acting aggressive, being angry or violent
Acting on dangerous impulses

Bupropion Dosage Information

Bupropion Dosage & Frequency

Typical Bupropion Dosage & Frequency

Individualized Dosage
As Needed

References

https://medlineplus.gov/druginfo/meds/a695033.html
https://medlineplus.gov/druginfo/meds/a695033.html
https://www.ncbi.nlm.nih.gov/books/NBK470212/
https://www.ncbi.nlm.nih.gov/books/NBK470212/
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ed2da3a6-0614-4bea-8e82-962cbaae6428
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ed2da3a6-0614-4bea-8e82-962cbaae6428
https://pubmed.ncbi.nlm.nih.gov/12376586/
https://pubmed.ncbi.nlm.nih.gov/12376586/
https://www.sciencedirect.com/science/article/pii/S0149291800883010
https://www.sciencedirect.com/science/article/pii/S0149291800883010
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1163271/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1163271/
https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2002.86
https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2002.86

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