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6 Surprising Benefits of Lipo B12 Injections

6 Surprising Benefits of Lipo B12 Injections

Lipotropics are nutrients that promote fat release and removal from the liver. Vitamin B12 is a water-soluble vitamin that is essential for healthy nerve function and red blood cell formation. Some of the most common lipotropics people use to supplement include:

  • Betaine
  • Branched-chain amino acids
  • Choline
  • Inositol
  • L-carnitine
  • Methionine
  • Vitamin B12
  • Vitamin B6

Lipotropics are used to enhance fat loss. People use them to complement a low-calorie diet and exercise program as part of a weight loss or weight management plan. Invigor Medical’s Lipo B12 contains methionine, inositol, and choline with vitamin B12. Lipo-B12 injections have the following potential benefits.

1. Support Fat Metabolism

Lipotropics help move fat and bile from the liver. When there is excess fat in your liver, your metabolism may slow as your body uses fat less efficiently for fuel. Methionine is converted to homocysteine and SAM, a methyl donor that is involved in many steps in fat metabolism.

2. Improve Liver Health

Inositol and methionine help with fat metabolism in the liver and support the movement of fat and bile from the liver. When fat and bile become trapped in the liver, they can damage liver tissue, a condition called cirrhosis. Methionine also supports liver health by deactivating estrogens. Estrogen reduces bile flow through the liver and increases bile cholesterol levels.

Choline deficiency can increase your risk for nonalcoholic fatty liver disease (NAFLD). This abnormal accumulation of fat in the liver causes fatty liver, liver damage, and sometimes, muscle damage. It affects nearly one in four people in the U.S. and other Western countries.1

In one study, 77% of men and 80% of postmenopausal women with choline deficiency developed fatty liver or muscle damage.2 An increase in liver fat is associated with an increase in oxidative stress, inflammation, and chronic kidney disease, all of which are strongly linked to overweight and obesity.1

3. Improve Blood Sugar

Research suggests that inositol may treat insulin resistance by restoring insulin sensitivity, especially in women with polycystic ovary syndrome (PCOS). PCOS is associated with abnormal glucose metabolism, reduced insulin sensitivity, and elevated fasting blood sugar.3

Inositols appear to be mediators of insulin action. An inositol deficit could contribute to the development or progression of insulin resistance, which contributes to type 2 diabetes, PCOS symptoms, metabolic syndrome, abnormal blood lipids, and obesity.4

4. Support Weight Loss

Inositol is a naturally occurring sugar that contributes to cell structure, metabolism, fat burning, energy storage, efficient energy consumption, and the stress response. Inositol helps move fats and bile out of the liver.

In one study, 22 female athletes who supplemented their diet with choline had greater weight loss than those who did not. Reduced body fat accounted for most of their weight loss. Other studies have shown inconsistent results when using lipotropics for weight loss.5

exercise to build bone density

5. Increase Energy Levels

For many reasons, vitamin B12 deficiency is common. Vitamin B12 deficiency is associated with several non-specific symptoms that affect nearly all body organs. Vitamin B12 is essential for growth, cellular reproduction, blood formation, neurological function, and DNA and protein synthesis. Replenishing vitamin B12 levels helps form healthy red blood cells that carry oxygen to body tissues. Efficient metabolism, nerve conduction, and oxygen transport help your body use the fuel you give it to provide long-lasting energy.

6. Reduce Inflammation

Research suggests that consuming diets rich in choline and betaine can decrease markers of inflammation. People who consumed the most choline had the biggest improvement in inflammatory markers such as adiponectin, high-molecular-weight adiponectin, resistin, and CRP.6

weight loss foods and tools

Lipotropics help move fat and bile from the liver, improving fat metabolism. When fat deposits increase in the liver, it is associated with an increase in oxidative stress and inflammation. This slows metabolism and is associated with weight gain. Increased organ fat or visceral obesity also increases your risk for type 2 diabetes, abnormal blood lipids, and insulin resistance.1

Lipotropic injections are prescription only. If you have questions about lipo-B12 injections and how they may support your weight loss efforts, contact one of the treatment specialists at Invigor Medical.

Learn more about buying Lipo B12 injections online.


While we strive to always provide accurate, current, and safe advice in all of our articles and guides, it’s important to stress that they are no substitute for medical advice from a doctor or healthcare provider. You should always consult a practicing professional who can diagnose your specific case. The content we’ve included in this guide is merely meant to be informational and does not constitute medical advice.


1. Chang TY, Wu CH, Chang CY, Lee FJ, Wang BW, Doong JY, Lin YS, Kuo CS, Huang RS. Optimal Dietary Intake Composition of Choline and Betaine Is Associated with Minimized Visceral Obesity-Related Hepatic Steatosis in a Case-Control Study. Nutrients. 2022 Jan 8;14(2):261. doi: 10.3390/nu14020261. PMID: 35057441; PMCID: PMC8779168.

2. Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu TS, Stabler SP, Allen RH, Zeisel SH. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007 May;85(5):1275-85. doi: 10.1093/ajcn/85.5.1275. PMID: 17490963; PMCID: PMC2435503.

3. Cianci A, Vitale SG. D-Chiro-inositol and PCOS: between myth and reality. The never-ending story. Int J Food Sci Nutr. 2022 Aug;73(5):565-570. doi: 10.1080/09637486.2022.2029830. Epub 2022 Jan 20. PMID: 35057707.

4. Caputo M, Bona E, Leone I, Samà MT, Nuzzo A, Ferrero A, Aimaretti G, Marzullo P, Prodam F. Inositols and metabolic disorders: From farm to bedside. J Tradit Complement Med. 2020 Mar 24;10(3):252-259. doi: 10.1016/j.jtcme.2020.03.005. PMID: 32670820; PMCID: PMC7340869.

5. Mah E, Chen O, Liska DJ, Blumberg JB. Dietary Supplements for Weight Management: A Narrative Review of Safety and Metabolic Health Benefits. Nutrients. 2022 Apr 24;14(9):1787. doi: 10.3390/nu14091787. PMID: 35565754; PMCID: PMC9099655.

6. Zeisel SH, da Costa KA. Choline: an essential nutrient for public health. Nutr Rev. 2009 Nov;67(11):615-23. doi: 10.1111/j.1753-4887.2009.00246.x. PMID: 19906248; PMCID: PMC2782876.

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Published: Jun 19, 2023


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