Author: Leann Poston, M.D.

testosterone chemical formula

What Happens When a Man’s Testosterone is Low?

Up to five million men in the United States have low testosterone. Unfortunately, aging is a major risk factor for testosterone decline. After the age of 30, testosterone drops by about 1% per year. When testosterone levels fall below 300 nanograms per deciliter (ng/dl) in a man with symptoms consistent with low testosterone, this is referred to as male hypogonadism. The prevalence of hypogonadism increases with aging, obesity, diabetes, and other metabolic and age-related conditions.  Restoring...

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anti-aging

Future Anti-aging Technology: Is Age Reversal Really Possible?

If we accept aging as a fact of life and inevitable, then there is nothing we can do to slow or even stop the process. However, considering the possibility that aging has a cause means there is the potential to identify the cause(s) and reverse or at least mitigate its effects.  Aging is the sum of all the bodily changes that occur throughout your lifespan. How fast these changes occur and how they present themselves differs from person to person.1 Healthy lifestyle choices can slow the...

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lady with wrinkles

What Causes Skin Wrinkles and How To Treat Them

Wrinkles are a visible reminder to yourself and others that you are getting older. Most of us dislike acknowledging this inevitable process. People in the United States spend over 50 billion dollars annually on anti-aging products, medications, and procedures.  Before there were effective treatment options, your only choice was to accept that your skin thins, sags, wrinkles, and accumulates age spots, but today many people are seeking age management treatment options.  Exposure...

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woman with supplements

Can Vitamin Supplements Improve Overall Brain Health?

Supplements are nutrients and vitamins people take to mitigate the effects of an imperfect diet or increased needs due to chronic disease or aging. Over 170 million Americans take dietary supplements. Top reasons for taking supplements include overall health and wellness benefits, increased energy, filling a nutrition gap, bone health, heart health, and healthy aging.  Research on supplements has exploded over the past two decades. However, it is a tough field to study as nutrients and...

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mental health

How Do Brain Health and Mental Health Intersect?

For most other body organs, it is straightforward to understand the relationship between the physical organ and the diseases that impact it. For example, when fluid fills the lungs, the fluid can become infected, and we call this pneumonia. The medical workup to diagnose pneumonia is pretty standard, as are the treatment options. So why is the relationship between brain health and mental health so murky? Our current understanding of mental illnesses is that they are conditions that negatively...

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metformin

How Does Metformin Contribute to Anti-Aging?

Anti-aging is not just about looking better. Although that is important for many people, it is also about living a healthier life longer. As a population, we are living longer, and you want those additional years to be healthy ones that allow you to be active and disease-free. The World Health Organization now formally recognizes aging as a disease in its latest International Classification of Diseases, which opens the door for developing therapeutic interventions that specifically target aging...

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women preventing aging

What Are the Health Benefits of NAD+ Therapy?

Nicotinamide adenine dinucleotide (NAD+) is a universal cellular electron transporter that transfers energy from the macronutrients in foods to cells in your body where it can be used for energy. There is a lot of supporting evidence that NAD+ plays a key role in longevity and long-term cellular health. A quick search on ClinicalTrials.gov yields over 1,000 clinical trials investigating the role of NAD+ in preventing and treating disease. NAD+ is a cofactor for many chemical reactions, including...

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anti-aging

When to Start Thinking About Anti-Aging

Do you want to look and feel younger? You are not alone. By 2030, the anti-aging market is expected to grow to around $119.6 billion. Treatment options for a more youthful appearance are far more comprehensive than ever before. Prices range from super-expensive plastic surgery to much more affordable anti-aging creams and supplements. So why is the market expanding so quickly? People are thinking about anti-aging long before that first wrinkle or smile line appears. When is the best time to think...

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older woman looking at a skeleton

Do You Get Shorter as You Age?

Do you get shorter as you age? Unfortunately, the answer is yes. According to researchers, the process starts after age 30. The change is not dramatic, only an inch or two, unless you have a medical condition called osteoporosis. Osteoporosis is decreased bone density. It increases your risk of hip and spine fractures. Spine and hip fractures can cause chronic pain and disability. If you are over 50, it is worth tracking your height periodically because osteoporosis doesn’t have any symptoms in...

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aging woman

Aging Differences by Sex and Gender

Women live longer than men. Why? There have been several theories, including estrogen protection against cardiovascular disease, a less risky lifestyle, and a willingness to seek preventative medical care. These factors may explain lifespan differences in some cases, but are unlikely to explain a persistent difference between men’s and women’s lifespans. The biggest factor affecting how men and women age and why they age differently is sex hormones. Testosterone levels slowly decline...

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endocrine system labs

What Is Hormonal Aging?

The endocrine and nervous systems work together to control almost all bodily functions. The nervous system acts quickly and precisely, while the endocrine system works more slowly. Together, these two systems work to keep your body in a steady state. Endocrine glands throughout the body release chemical messengers called hormones. These hormones bind to receptors on target cells, where they produce a response. The same hormone may produce very different responses depending on the target cell with...

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weight loss medications

Where can I buy Liraglutide Online?

Results from the National Health and Nutrition Survey showed that almost one-half of US adults were trying to lose weight in the 12 months before the survey. More women (56.4%) admitted to working hard to shed those excess pounds than men (41.7%). Weight loss strategies included: Exercising (62.9%) Cutting calories (62.9%) Eating healthier foods (50.4%) Novo Nordisk is a pharmaceutical company that has noticed the demand for weight loss products and has made a concerted effort to provide weight...

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weight loss medications

Where can I get semaglutide online? 

Semaglutide is the “generic name” for Ozempic, Rybelsus, and Wegovy. Novo Nordisk manufactures all three brand-name medications. Ozempic and Rybelsus are FDA-approved to treat type-2 diabetes, and Wegovy is FDA-approved for long-term weight management. Since the FDA-approved Wegovy in 2021 for adults with overweight and obesity, there has been a lot of online conversation about these three drugs. The demand for Wegovy has been so high that there are shortages. This leads many people to ask questions....

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doctor and weight loss

Should I buy Ozempic from Canada?

Many people are talking about Wegovy and how well it works for weight loss. But, they are also talking about the price. According to the manufacturer, Novo Nordisk, Wegovy, generic name semaglutide, has a list price of $1,349.02. Unfortunately, this hefty price tag is out of most people’s reach, leading them to consider alternatives. Most people in the US and abroad look at the prices of American healthcare and pharmaceuticals and shake their heads. So what are the alternatives?  Wegovy...

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decreased bone density

Can Your Skeleton Shrink as a Result of Weight Loss?

While your bones don’t shrink when you lose weight, they can lose density, which is a significant health concern. Weight loss affects bone density, causing bones to be thinner and lighter, increasing your risk for bone fractures.  The global prevalence of obesity has nearly doubled since the 1980s. Obesity increases the risk of developing chronic medical conditions such as cardiovascular disease and diabetes. Restricting calories can support weight loss efforts, but it is important...

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man with balding and gray hair

At What Age Do Males Turn Gray and Lose Hair?

Hair color and fullness have long been a symbol of youth and vitality. Many factors determine when men turn gray and lose their hair. Male pattern baldness, or androgenic alopecia, affects about 50 million men and 30 million women in the US. Finasteride, a medication that reduces hair loss and increases hair regrowth, works best when you are just starting to lose hair. So, while the causes of gray hair and balding are not completely understood, it is good to know when male pattern baldness will...

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age-related brain changes

How Does Aging Affect the Nervous System?

Sometimes it’s hard to separate the nervous system, an organ system like any other in the body, from your sense of self. While your brain is indeed a collection of cells, just like the liver and the heart, the fact that it controls memory, personality, and feelings, not to mention movement and sensation, makes it feel like the nervous system should be elevated to a level above the other organ systems.  The nervous system, made up of the brain, spinal cord, and a network of nerve cells...

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Online reviews

Wegovy Reviews: How Effective Is It Really?

Wegovy is a prescription injectable medication that is U.S. Food and Drug Administration (FDA) approved for weight management. Novo Nordisk is the manufacturer of Wegovy and the following medications, which all contain semaglutide. Ozempic Rybelsus Liraglutide Based on the results of the Semaglutide Treatment Effect in Obese People (STEP) clinical trial, the FDA gave Wegovy its approval. The STEP clinical trials were a series of four 68-week randomized, double-blind clinical trials that enrolled...

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Wegovy injection

Wegovy Dosing Instructions: Keeping it Simple

Wegovy (generic name semaglutide) is in a family of medications called glucagon-like peptide 1 receptor (GLP-1) agonists. Novo Nordisk, the manufacturer, first developed this class of medications to treat type 2 diabetes. When researchers found that, besides reducing blood glucose, semaglutide caused significant weight loss, they explored the possibility of using semaglutide as a medication for long-term weight management. After a series of clinical trials demonstrating its effectiveness and safety,...

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weight loss cost

What Does Wegovy Cost: Is the Price Really Worth It?

According to manufacturer Novo Nordisk, Wegovy (semaglutide) has a list price of $1,349.02 per package. A package is four pre-loaded pens that provide a month’s supply of the medication. Wegovy is taken as a once-weekly, subcutaneous (under the skin) injection. The $1,349.02 price tag is the list price not the cost to the consumer and it is before any medication discounts or rebates are applied. Why Does Wegovy (Semaglutide) Cost so Much? According to the Centers for Medicare and Medicaid (CMS),...

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